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单侧腰麻与连续腰麻硬膜外联合麻醉用于下肢骨科手术的疗效及安全性比较

Comparison of Efficacy and Safety of Unilateral Spinal Anaesthesia with Sequential Combined Spinal Epidural Anaesthesia for Lower Limb Orthopaedic Surgery.

作者信息

Magar Jyoti Sandeep, Bawdane Kishori Dhaku, Patil Rahul

机构信息

Associate Professor, Department of Anaesthesia, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.

Assistant Professor, Department of Anaesthesia, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.

出版信息

J Clin Diagn Res. 2017 Jul;11(7):UC17-UC20. doi: 10.7860/JCDR/2017/26235.10215. Epub 2017 Jul 1.

Abstract

INTRODUCTION

Orthopaedic anaesthesia plan requires customi-zation as per patient's need for safe outcome. Sequential Combined Spinal Epidural Anaesthesia (Sequential CSEA) and Unilateral Single Shot Spinal anaesthesia (Unilateral SA), both have advantages over conventional spinal anaesthesia that they provide longer lasting block with less hypotension.

AIM

To compare safety and efficacy of unilateral spinal anaesthesia with sequential combined spinal epidural anaesthesia for lower limb orthopaedic surgery .

MATERIALS AND METHODS

This prospective randomized study was conducted on sixty ASA I-III patients aged 18- 65 years undergoing lower limb orthopaedic surgeries of approximately two hours duration. Sequential CSE group received spinal with 5 mg of 0.5 hyperbaric bupivacaine followed by incremental epidural top up of 2 cc of 0.5% isobaric bupivacaine to achieve and maintain T10 level. In unilateral SA group, unilateral spinal anaesthesia was given with 10 mg of 0.5% hyperbaric bupivacaine. Haemodynamic parameter, anaesthesia readiness time and block characteristics were recorded and results were analysed using unpaired Student's t-test.

RESULTS

There was no failure of block, surgical anaesthesia with T10 sensory level and bromage score three motor block was achieved by all patients in both groups. Anaesthesia readiness time was less in unilateral SA (p<0.001) Incidences of hypotension (p-value 0.0059) and mean ephedrine dose were significantly less in sequential CSEA. Five patients of unilateral SA required supplementation with general anaesthesia.

CONCLUSION

Thus, our study concludes that unilateral SA is a cost-effective and rapidly performed anaesthetic technique. Unilateral SA with 10 mg bupivacaine and sequential CSEA with 5 mg spinal and incremental epidural top up, both provide good quality sensory and motor block for lower limb orthopaedic surgery but sequential CSEA provides significantly more stable haemodynamics with feasibility to prolong block. Thus sequential CSEA should be preferred over unilateral SA in high risk patients especially for major lower limb orthopaedic surgeries.

摘要

引言

骨科麻醉方案需要根据患者需求进行定制,以确保安全的手术结果。序贯联合蛛网膜下腔硬膜外麻醉(序贯CSEA)和单侧单次蛛网膜下腔麻醉(单侧SA)相较于传统蛛网膜下腔麻醉均具有优势,它们能提供更持久的阻滞,且低血压发生率更低。

目的

比较单侧蛛网膜下腔麻醉与序贯联合蛛网膜下腔硬膜外麻醉在下肢骨科手术中的安全性和有效性。

材料与方法

本前瞻性随机研究纳入了60例年龄在18至65岁之间、美国麻醉医师协会(ASA)分级为I - III级、接受时长约两小时下肢骨科手术的患者。序贯CSE组先给予5mg 0.5%的重比重布比卡因进行蛛网膜下腔麻醉,随后追加2ml 0.5%的等比重布比卡因进行硬膜外麻醉,以达到并维持T10节段的麻醉平面。单侧SA组给予10mg 0.5%的重比重布比卡因进行单侧蛛网膜下腔麻醉。记录血流动力学参数、麻醉准备时间和阻滞特征,并采用非配对学生t检验分析结果。

结果

两组患者均未出现阻滞失败情况,所有患者均达到了T10感觉平面的手术麻醉效果及布罗玛杰评分三级的运动阻滞效果。单侧SA组的麻醉准备时间更短(p<0.001)。序贯CSEA组的低血压发生率(p值为0.0059)和麻黄碱平均用量显著更低。单侧SA组有5例患者需要补充全身麻醉。

结论

因此,我们的研究得出结论,单侧SA是一种经济高效且实施迅速的麻醉技术。10mg布比卡因的单侧SA和5mg蛛网膜下腔麻醉并追加硬膜外麻醉的序贯CSEA,均能为下肢骨科手术提供良好的感觉和运动阻滞效果,但序贯CSEA能提供更稳定的血流动力学,且具备延长阻滞时间的可行性。因此,在高危患者中,尤其是对于大型下肢骨科手术,序贯CSEA应优先于单侧SA。

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