Peacock Zachary S
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Warren 1201, 55 Fruit Street, Boston, MA 02114, USA.
Oral Maxillofac Surg Clin North Am. 2017 Nov;29(4):475-486. doi: 10.1016/j.coms.2017.06.005.
Several benign pathologic entities that are commonly encountered by the oral and maxillofacial surgeon remain controversial. From etiology to treatment, no consensus exists in the literature regarding the best treatment of benign lesions, such as the keratocystic odontogenic tumor, giant cell lesion, or ameloblastoma. Given the need for often-morbid treatment to prevent recurrence of these lesions, multiple less-invasive treatments exist in the literature for each entity with little agreement. As the molecular and genomic pathogenesis of these lesions are better understood, directed treatments will hopefully lessen the contention in management.
口腔颌面外科医生常见的几种良性病理实体仍存在争议。从病因到治疗，文献中对于良性病变（如角化囊性牙源性肿瘤、巨细胞病变或成釉细胞瘤）的最佳治疗方法尚无共识。鉴于需要采用往往具有致残性的治疗来预防这些病变的复发，文献中针对每种实体都存在多种侵入性较小的治疗方法，但几乎没有达成一致意见。随着对这些病变的分子和基因组发病机制有了更好的理解，针对性治疗有望减少治疗中的争议。
