Martinelli Ombretta, Faccenna Federico, Malaj Alban, Jabbour Jihad, Venosi Salvatore, Gattuso Roberto, Gossetti Bruno, Irace Luigi
Department of General Surgery, Surgical Specialties and Organ Transplantation "Paride Stefanini", Policlinico "Umberto I" Hospital, "Sapienza" University, Rome, Italy.
Department of General Surgery, Surgical Specialties and Organ Transplantation "Paride Stefanini", Policlinico "Umberto I" Hospital, "Sapienza" University, Rome, Italy; PhD programme in FISIOPATOLOGIA ED IMAGING CARDIO-TORACO- VASCOLARE (31° ciclo), PhD coordinator: Prof. Federico Venuta, Rome, Italy.
Ann Vasc Surg. 2018 Feb;47:281.e5-281.e10. doi: 10.1016/j.avsg.2017.08.041. Epub 2017 Sep 9.
Thoracic endovascular aortic repair (TEVAR) is a less invasive option for managing traumatic injuries of the descending aorta in polytraumatized patients. Concerns arise when treating young patients with TEVAR. A 22-year-old male was admitted to the emergency department following a high-impact road traffic collision. Whole-body computed tomography (CT) scan documented multiple injuries, including rupture of descending thoracic aorta just below the isthmus. There was no evidence of paraplegia or stroke. We decided to treat him in an endovascular fashion with a Zenith Cook (Cook Incorporated, Bloomington, IN) endograft. Final angiography confirmed the proper positioning of the device, no infoldings, and the optimal filling of the thoracic aorta downstream of the endoprosthesis. In the postoperative period, the patient showed high blood pressure which was treated with 4 different antihypertensive drugs. He was discharged on cardioaspirine. CT scan control was scheduled after 30 days and 6 months, but he referred to our emergency department after less than 6 months with paraplegia, abdominal pain, and acute renal failure. He had independently discontinued antiplatelet therapy 3 months before. Emergency CT control documented the presence of intimal flap and thrombus at the distal edge of the device. The magnetic resonance imaging revealed ischemic damage of the spinal cord. We decided to reline the endograft using another Zenith Cook device with very good results. Renal failure and bowel pain gradually improved, but paraplegia is still present. TEVAR is the most suitable treatment for blunt thoracic aortic injury in the modern era. Concerns arise from what can happen to a young aorta receiving a stiff endovascular graft that should be carried all lifelong. These devices have been associated with acute hypertension and cardiac remodeling. Less stiffer stent grafts should be studied for young patients. High attention must be posed in the follow-up for the immediate resolution of eventual problems.
胸主动脉腔内修复术(TEVAR)是治疗多发伤患者降主动脉创伤性损伤的一种侵入性较小的选择。在治疗年轻患者时使用TEVAR会引发一些担忧。一名22岁男性在发生严重道路交通事故后被送往急诊科。全身计算机断层扫描(CT)显示多处损伤,包括峡部下方降主动脉破裂。没有截瘫或中风的迹象。我们决定采用Cook公司的Zenith(印第安纳州布卢明顿市库克公司)血管内移植物对他进行血管内治疗。最终血管造影证实了装置的正确定位、无褶皱以及血管内假体下游胸主动脉的最佳充盈情况。术后,患者出现高血压,使用4种不同的抗高血压药物进行治疗。他出院时服用了抗血小板药物。计划在30天和6个月后进行CT扫描复查,但他在不到6个月时因截瘫、腹痛和急性肾衰竭前来我们的急诊科就诊。他在3个月前自行停止了抗血小板治疗。急诊CT检查发现装置远端边缘存在内膜瓣和血栓。磁共振成像显示脊髓有缺血性损伤。我们决定使用另一个Zenith Cook装置对血管内移植物进行重新内衬,效果非常好。肾衰竭和腹痛逐渐改善,但截瘫仍然存在。TEVAR是现代治疗钝性胸主动脉损伤最合适的方法。对于年轻的主动脉植入一个终身携带的硬血管内移植物可能发生的情况令人担忧。这些装置与急性高血压和心脏重塑有关。对于年轻患者,应研究更柔软的支架型人工血管。在随访中必须高度关注,以便立即解决可能出现的问题。