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Human T-cell lymphotropic virus type I-associated adult T-cell leukemia/lymphoma in an atypical host.

作者信息

Goldman-Leikin R E, Herst C V, Kies M S, Variakojis D, Marder R J, Rosen S T

机构信息

Section of Medical Oncology, Northwestern University, Chicago, IL.

出版信息

Arch Pathol Lab Med. 1987 Nov;111(11):1054-6.

PMID:2889441
Abstract

Human T-cell lymphotropic virus type I (HTLV-I) is a unique retrovirus associated with specific malignancies of T cells in humans. The virus is endemic to Japan, the Caribbean, Africa, and the southeastern United States. We report here the first case of HTLV-I-associated lymphoma in an atypical host. The incidence of antibodies in this individual with a T-cell malignancy strongly suggests HTLV-I virus as the causative agent. Direct identification of viral DNA using an HTLV-I-specific probe provides definitive evidence of infection.

摘要

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