Beyea Jason A, Nguyen Paul, Hall Stephen F
Department of Otolaryngology, Hotel Dieu Hospital, Queen's University, Kingston, Ontario, Canada.
Institute for Clinical Evaluative Sciences (ICES), Queen's University, Kingston, Ontario, Canada.
Laryngoscope. 2018 Apr;128(4):991-997. doi: 10.1002/lary.26889. Epub 2017 Sep 12.
To characterize risk factors that predict the need for multiple tympanostomy tube (TT) procedures.
Retrospective population-based cohort study of children aged 18 years and younger in Ontario, Canada, who underwent at least one TT placement between January 1, 1994, and October 31, 2013.
The relative risk (RR) of need for multiple TT procedures was determined using log-binomial regression.
There were 193,880 children who underwent TT insertion included in this cohort. Of these, 28.58% underwent at least two separate TT procedures. Over time, the RR of undergoing multiple TT procedures is decreasing for all children. In general, the younger the child was at the first TT procedure, the more likely the child was to undergo multiple TT procedures. Significantly higher RR for multiple TT procedures also was associated with male sex, the second-highest neighborhood income quintile, asthma or reactive airways, gastrointestinal disease, prematurity, or cleft lip and/or palate. Significantly lower RR for multiple TT procedures was associated with adenoidectomy or tonsillectomy (with or without adenoidectomy) at first TT placement or within 3 years prior. Furthermore, the benefit of adjuvant adenoidectomy or tonsillectomy was present for children aged under 4 years, in addition to those aged 4 years and older.
Among Ontario children who have had TT placement, more than one in four will have multiple sets placed. These identified risk factors permit improved preoperative counseling and enable identification of children who need closer follow-up.
2b. Laryngoscope, 128:991-997, 2018.
确定预测多次鼓膜置管(TT)手术需求的风险因素。
对1994年1月1日至2013年10月31日期间在加拿大安大略省接受至少一次TT置管的18岁及以下儿童进行基于人群的回顾性队列研究。
使用对数二项回归确定多次TT手术需求的相对风险(RR)。
该队列中有193,880名儿童接受了TT置入。其中,28.58%的儿童接受了至少两次单独的TT手术。随着时间的推移,所有儿童接受多次TT手术的RR都在下降。一般来说,首次进行TT手术时年龄越小的儿童,越有可能接受多次TT手术。多次TT手术的RR显著升高还与男性、邻里收入第二高的五分位数、哮喘或反应性气道疾病、胃肠道疾病、早产或唇裂和/或腭裂有关。多次TT手术的RR显著降低与首次TT置管时或之前3年内进行腺样体切除术或扁桃体切除术(无论是否同时进行腺样体切除术)有关。此外,辅助性腺样体切除术或扁桃体切除术对4岁及以上儿童以及4岁以下儿童均有益。
在安大略省接受TT置管的儿童中,超过四分之一的儿童将接受多次置管。这些确定的风险因素有助于改善术前咨询,并能够识别需要密切随访的儿童。
2b。《喉镜》,2018年,第128卷,第991 - 997页。