Nwafor C Ikenna, Plant Kevin D, King Darlene R, McCall Brian P, Squiers John J, Fan Wensheng, DiMaio J Michael, Thatcher Jeffrey E
Spectral MD, Inc., Texas, United States.
Baylor University Medical Center, Department of Surgery, Texas, United States.
J Biomed Opt. 2017 Sep;22(9):1-9. doi: 10.1117/1.JBO.22.9.096003.
Noncontact photoplethysmography (PPG) has been studied as a method to provide low-cost, noninvasive, two-dimensional blood oxygenation measurements and medical imaging for a variety of near-surface pathologies. To evaluate this technology in a laboratory setting, dynamic tissue phantoms were developed with tunable parameters that mimic physiologic properties of the skin, including blood vessel volume change, pulse wave frequency, and tissue scattering and absorption. Tissue phantoms were generated using an elastic tubing to represent a blood vessel where the luminal volume could be modulated with a pulsatile fluid flow. The blood was mimicked with a scattering and absorbing motility standard, and the tissue with a gelatin-lipid emulsion hydrogel. A noncontact PPG imaging system was then evaluated using the phantoms. Noncontact PPG imaging accurately identified pulse frequency, and PPG signals from these phantoms suggest that the phantoms can be used to evaluate noncontact PPG imaging systems. Such information may be valuable to the development of future PPG imaging systems.
非接触式光电容积脉搏波描记法（PPG）已被作为一种方法进行研究，用于为各种近体表病变提供低成本、非侵入性的二维血氧测量和医学成像。为了在实验室环境中评估该技术，开发了具有可调参数的动态组织模型，这些参数可模拟皮肤的生理特性，包括血管容积变化、脉搏波频率以及组织散射和吸收。使用弹性管来代表血管生成组织模型，其中管腔容积可通过脉动流体流动进行调节。血液用具有散射和吸收特性的运动标准物模拟，组织用明胶 - 脂质乳液水凝胶模拟。然后使用这些模型对非接触式PPG成像系统进行评估。非接触式PPG成像准确识别了脉搏频率，并且来自这些模型的PPG信号表明这些模型可用于评估非接触式PPG成像系统。此类信息对于未来PPG成像系统的开发可能具有重要价值。
