Department of Rehabilitation Science and Technology, School of Health and Rehabilitation Science, University of Pittsburgh, Pittsburgh, PA, USA.
McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Spinal Cord. 2018 Jan;56(1):28-34. doi: 10.1038/sc.2017.96. Epub 2017 Sep 12.
Secondary analysis of data from a prospective cohort study.
The objective of this study was to identify the medical and demographic factors associated with the development of pressure ulcers during acute-care hospitalization and inpatient rehabilitation following acute spinal cord injury.
The study was carried out at acute hospitalization, inpatient rehabilitation and outpatient rehabilitation sites at a university medical center in the United States.
Adults with acute traumatic spinal cord injury (n=104) were recruited within 24-72 h of admission to the hospital. Pressure ulcer incidence was recorded.
Thirty-nine participants out of 104 (37.5%) developed at least one pressure ulcer during acute-care hospitalization and inpatient rehabilitation. Univariate logistic regression analyses revealed significant association of pressure ulcer incidence for those with pneumonia and mechanical ventilation (P=0.01) and higher injury severity (ASIA A) (P=0.01). Multiple logistic regression showed that the odds of formation of a first pressure ulcer in participants with ASIA A was 4.5 times greater than that for participants with ASIA B, CI (1-20.65), P=0.05, and 4.6 times greater than that for participants with ASIA C, CI (1.3-16.63), P=0.01.
Among individuals with acute traumatic SCI, those with high-injury severity were at an increased risk to develop pressure ulcers. Pneumonia was noted to be associated with the formation of pressure ulcers.
前瞻性队列研究数据的二次分析。
本研究旨在确定与急性脊髓损伤后急性住院和住院康复期间发生压力性溃疡相关的医学和人口统计学因素。
该研究在美国一所大学医学中心的急性住院、住院康复和门诊康复场所进行。
在入院后 24-72 小时内招募了 104 名急性创伤性脊髓损伤的成年人。记录压力性溃疡的发生率。
在 104 名参与者中,有 39 名(37.5%)在急性住院和住院康复期间至少发生了一次压力性溃疡。单变量逻辑回归分析显示,患有肺炎和机械通气的患者(P=0.01)和损伤严重程度较高(ASIA A)(P=0.01)的压力性溃疡发生率存在显著关联。多变量逻辑回归显示,ASIA A 组参与者首次发生压力性溃疡的可能性是 ASIA B 组参与者的 4.5 倍,CI(1-20.65),P=0.05,是 ASIA C 组参与者的 4.6 倍,CI(1.3-16.63),P=0.01。
在急性创伤性脊髓损伤患者中,损伤严重程度较高的患者发生压力性溃疡的风险增加。肺炎被认为与压力性溃疡的形成有关。