a Associate Professor, Department of Population Health , New York University Langone Medical Center , New York, NY , USA.
b Project Manager and Graduate Student, College of Global Public Health , New York University , New York , NY , USA.
J Psychoactive Drugs. 2018 Apr-Jun;50(2):159-166. doi: 10.1080/02791072.2017.1368747. Epub 2017 Sep 12.
Nonmedical opioid use has been linked to lifetime heroin use; however, research is needed to examine associations between nonmedical opioid use and current or recent heroin use, as current users appear to be at highest risk for harm. Data were from a nationally representative sample of non-institutionalized adults (age 18-64) in households participating in the National Survey of Drug Use and Health who reported lifetime heroin use (2005-2014, N = 7,111). We examined associations between frequency and recency of nonmedical opioid use and recency of heroin use. Most (86.7%) lifetime heroin users reported no heroin use in the last 12 months, while 6.1% reported current use (use in the last 30 days). The majority of the sample (69.3%) reported lifetime nonmedical opioid use; 14.3% reported nonmedical use in the last 30 days. Adjusted odds for current heroin use increased as frequency of past-year nonmedical opioid use increased, with a quarter (24.7%) of current heroin users reporting nonmedical opioid use on 157-365 days in the last year. Over half (54.7%) of current heroin users reported current nonmedical opioid use. Prevention efforts should consider that high-frequency and current nonmedical opioid use is a robust correlate of continued heroin use.
非医疗用途的阿片类药物使用与终身使用海洛因有关;然而,需要开展研究以检验非医疗用途阿片类药物使用与当前或近期海洛因使用之间的关联,因为当前使用者似乎面临着最高的伤害风险。数据来自参与国家药物使用和健康调查的非机构化成年人群体(18-64 岁)的全国代表性样本,这些人报告了终身使用海洛因(2005-2014 年,N=7111)。我们检验了非医疗用途阿片类药物使用的频率和近期使用情况与近期海洛因使用情况之间的关联。大多数(86.7%)终身海洛因使用者报告在过去 12 个月内没有使用过海洛因,而 6.1%的人报告当前使用(在过去 30 天内使用)。样本的大多数(69.3%)报告了终身非医疗用途阿片类药物使用;14.3%的人报告在过去 30 天内有非医疗使用。过去一年中,过去一年中阿片类药物非医疗使用频率越高,当前海洛因使用的调整后比值比就越高,有四分之一(24.7%)的当前海洛因使用者报告在过去一年中阿片类药物非医疗使用了 157-365 天。超过一半(54.7%)的当前海洛因使用者报告当前正在使用非医疗用阿片类药物。预防工作应考虑到,高频和当前非医疗用途阿片类药物使用是持续使用海洛因的一个有力关联因素。