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[阻碍癫痫手术可及性的因素:文献综述]

[Barriers impeding access to epilepsy surgery: a review of the literature].

作者信息

Ladino L D, Benjumea-Cuartas V, Vargas-Osorio J, Villamil-Osorio L V, Hernandez-Vanegas L, Martinez-Juarez I E, Tellez-Zenteno J F

机构信息

University of Saskatchewan, Royal University Hospital , Saskatoon, Canada.

Programa de Epilepsia Hospital Pablo Tobon Uribe, Medellin, Colombia.

出版信息

Rev Neurol. 2017 Sep 16;65(6):268-279.

PMID:28896001
Abstract

Drug-resistant epilepsy, a chronic condition with long-term consequences can be treated with surgery. The efficacy and safety of surgery for temporal lobe epilepsy have been established through a large number of retrospective and prospective cohort studies and two randomized controlled clinical trials. Despite the excellent outcomes reported after surgery, the literature suggests that this procedure is an underutilized treatment. While evidence is lacking as to why epilepsy surgery is underused, cited reasons include: failure of primary care physicians and neurologists to provide information and identify patients who could be referred for surgery; different levels of technology at various centers, resulting in different candidate selection strategies; the belief that epilepsy surgery is a risky procedure and that it should be only viewed as the last option; patient preference to avoid surgery; parents wanting to wait until their child is old enough to participate in the decision-making process regarding surgery; unwillingness of insurers to cover the expenses associated with presurgical evaluations or lack of insurance; racial and social disparities, among others. In this paper we review the available epidemiological data about lack of utilization of epilepsy surgery.

摘要

耐药性癫痫是一种具有长期后果的慢性疾病,可通过手术进行治疗。颞叶癫痫手术的疗效和安全性已通过大量回顾性和前瞻性队列研究以及两项随机对照临床试验得以确立。尽管手术后报告了出色的结果,但文献表明该手术是一种未得到充分利用的治疗方法。虽然缺乏关于癫痫手术未得到充分利用原因的证据,但列举的原因包括:初级保健医生和神经科医生未能提供信息并识别可被转诊进行手术的患者;各中心技术水平不同,导致候选者选择策略各异;认为癫痫手术是一种有风险的手术,应仅被视为最后选择;患者倾向于避免手术;父母希望等到孩子足够大,能够参与有关手术的决策过程;保险公司不愿意承担与术前评估相关的费用或缺乏保险;种族和社会差异等。在本文中,我们回顾了有关癫痫手术未得到充分利用的现有流行病学数据。

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1
[Barriers impeding access to epilepsy surgery: a review of the literature].[阻碍癫痫手术可及性的因素:文献综述]
Rev Neurol. 2017 Sep 16;65(6):268-279.
2
Revisiting racial disparities in access to surgical management of drug-resistant temporal lobe epilepsy post implementation of Affordable Care Act.《平价医疗法案》实施后重新审视耐药性颞叶癫痫手术治疗可及性方面的种族差异
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Patient Historical Risk Factors Associated with Seizure Outcome After Surgery for Drug-Resistant Nonlesional Temporal Lobe Epilepsy.与药物难治性非病灶性颞叶癫痫手术后癫痫发作结果相关的患者历史风险因素。
World Neurosurg. 2016 Jul;91:205-9. doi: 10.1016/j.wneu.2016.04.022. Epub 2016 Apr 13.
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SEEG-guided radiofrequency coagulation (SEEG-guided RF-TC) versus anterior temporal lobectomy (ATL) in temporal lobe epilepsy.SEEG 引导下射频热凝术(SEEG-guided RF-TC)与前颞叶切除术(ATL)治疗颞叶癫痫的比较。
J Neurol. 2018 Sep;265(9):1998-2004. doi: 10.1007/s00415-018-8958-9. Epub 2018 Jun 26.
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[ Delay time from diagnosis to surgery in drug-resistant epilepsy].[耐药性癫痫从诊断到手术的延迟时间]
Rev Fac Cien Med Univ Nac Cordoba. 2022 Dec 21;79(4):405-407. doi: 10.31053/1853.0605.v79.n4.37485.
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Predictors of meaningful improvement in quality of life after temporal lobe epilepsy surgery: A prospective study.颞叶癫痫手术后生活质量有意义改善的预测因素:一项前瞻性研究。
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Predictors of outcome after surgery in 134 children with drug-resistant TLE.134例耐药性颞叶癫痫患儿术后预后的预测因素
Epilepsy Res. 2018 Jan;139:150-156. doi: 10.1016/j.eplepsyres.2017.11.020. Epub 2018 Jan 2.

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Neurosurg Rev. 2025 Jun 14;48(1):509. doi: 10.1007/s10143-025-03665-0.
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Epilepsy surgery education and practice around the globe: An ILAE taskforce report.全球癫痫手术教育与实践:国际抗癫痫联盟特别工作组报告
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[Neuropsychological profile of Mexican paediatric patients with pharmacoresistant focal epilepsy].[墨西哥药物难治性局灶性癫痫儿科患者的神经心理学概况]
Rev Neurol. 2024 Jun 16;78(12):343-354. doi: 10.33588/rn.7812.2024096.
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D-galactose Supplementation for the Treatment of Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE): A Pilot Trial of Precision Medicine After Epilepsy Surgery.半乳糖补充治疗癫痫伴少突胶质细胞增生性皮质发育不良轻度畸形(MOGHE):癫痫手术后精准医学的初步试验。
Neurotherapeutics. 2023 Sep;20(5):1294-1304. doi: 10.1007/s13311-023-01395-z. Epub 2023 Jun 6.