中心体生物学：基于聚合物的中心体成熟。

Centrosome Biology: Polymer-Based Centrosome Maturation.

机构信息

Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada.

Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, M5S 1A8, Canada.

出版信息

Curr Biol. 2017 Sep 11;27(17):R836-R839. doi: 10.1016/j.cub.2017.07.036.

DOI:10.1016/j.cub.2017.07.036

PMID:28898644

Abstract

The molecular mechanisms that control how the centrosome increases in size and microtubule nucleation capacity during mitosis have remained elusive. Recent work using in vitro assays provide exciting clues as to how this may occur.

摘要

控制中心体在有丝分裂过程中如何增加大小和微管核形成能力的分子机制一直难以捉摸。最近使用体外测定法的工作为了解这一过程提供了令人兴奋的线索。