Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Curr Biol. 2017 Sep 11;27(17):R844-R847. doi: 10.1016/j.cub.2017.07.030.
The pha-1 gene of Caenorhabditis elegans was originally heralded as a master regulator of organ differentiation. A new study suggests instead that pha-1 actually serves no role in development and instead is a component of a selfish genetic element.
秀丽隐杆线虫的 pha-1 基因最初被称为器官分化的主调控因子。一项新的研究表明,pha-1 实际上在发育过程中不起作用,而是一种自私遗传元件的组成部分。