Rouger Laetitia, Akoka Serge, Giraudeau Patrick
CNRS UMR 6230 CEISAM, Université de Nantes, Nantes, France.
CNRS UMR 6230 CEISAM, Université de Nantes, Nantes, France; Institut Universitaire de France, Paris, France.
J Magn Reson. 2017 Oct;283:89-95. doi: 10.1016/j.jmr.2017.08.015. Epub 2017 Sep 1.
Ultrafast (UF) 2D NMR, which enables the acquisition of 2D spectra within a single scan, is nowadays used in a large array of applications. However, the use of UF-HSQC experiments is still limited by the need to compromise between spectral widths and resolution. Interleaved acquisitions can overcome this limitation, albeit at the cost of strong artifacts. We show that the occurrence of these artifacts is mainly related to the discontinuous decoupling scheme which is generally used in UF-HSQC. In this paper, four continuous decoupling schemes using adiabatic pulses are optimized for this kind of experiments, giving access to full-range UF-HSQC spectra.
超快（UF）二维核磁共振（NMR）能够在单次扫描中获取二维谱，如今已在大量应用中得到使用。然而，UF-HSQC实验的应用仍受限于在谱宽和分辨率之间做出妥协的需求。交错采集可以克服这一限制，尽管代价是会产生严重的伪影。我们表明，这些伪影的出现主要与UF-HSQC中普遍使用的不连续去耦方案有关。本文针对此类实验优化了四种使用绝热脉冲的连续去耦方案，从而能够获得全范围的UF-HSQC谱。
