Moon Jin Hee, Hwang Ji-Young, Park Jeong Seon, Koh Sung Hye, Park Sun-Young
1 Department of Radiology, Kangnam Sacred Heart Hospital, Seoul, Republic of Korea.
2 Department of Radiology, Hanyang University, College of Medicine, Seoul, Republic of Korea.
Acta Radiol. 2018 Jun;59(6):657-663. doi: 10.1177/0284185117732097. Epub 2017 Sep 12.
Background Shear wave elastography (SWE) using a region of interest (ROI) can demonstrate the quantitative elasticity of breast lesions. Purpose To prospectively evaluate the impact of two different ROI sizes on the diagnostic performance of SWE for differentiating benign and malignant breast lesions. Material and Methods A total of 154 breast lesions were included. Two types of ROIs were investigated: one involving an approximately 2-mm diameter, small round ROIs placed over the stiffest area of the lesion, as determined by SWE (ROI-S); and another ROI drawn along the margin of the lesion using a touch pen or track ball to encompass the entire lesion (ROI-M). Maximum elasticity (E), mean elasticity (E), minimum elasticity (E), and standard deviation (SD) were measured for the two ROIs. The area under the receiver operating characteristic curve (AUC) as well as the sensitivity and specificity of each elasticity value were determined. Results The AUCs for ROI-S were higher than those for ROI-M when differentiating benign and malignant breast solid lesions. The E, E, E, and SD of the elasticity values for ROI-S were 0.865, 0.857, 0.816, and 0.849, respectively, and for ROI-M were 0.820, 0.780, 0.724, and 0.837, respectively. However, only E ( P = 0.0024) and E ( P = 0.0015) showed statistically significant differences. For ROI-S, the sensitivity and specificity of E were 78.8% and 84.3%, respectively, and those for E were 80.8% and 81.4%, respectively. Conclusion Using ROI-S with E and E has better diagnostic performance than ROI-M for differentiating between benign and malignant breast lesions.
背景 使用感兴趣区域（ROI）的剪切波弹性成像（SWE）可显示乳腺病变的定量弹性。目的 前瞻性评估两种不同ROI大小对SWE鉴别乳腺良恶性病变诊断性能的影响。材料与方法 共纳入154例乳腺病变。研究了两种类型的ROI：一种是直径约2毫米的小圆形ROI，放置在由SWE确定的病变最硬区域上（ROI-S）；另一种是使用触笔或轨迹球沿着病变边缘绘制的ROI，以包围整个病变（ROI-M）。测量了两种ROI的最大弹性（E）、平均弹性（E）、最小弹性（E）和标准差（SD）。确定了受试者操作特征曲线（AUC）下的面积以及每个弹性值的敏感性和特异性。结果 在鉴别乳腺良恶性实性病变时，ROI-S的AUC高于ROI-M。ROI-S弹性值的E、E、E和SD分别为0.865、0.857、0.816和0.849，ROI-M的分别为0.820、0.780、0.724和0.837。然而，只有E（P = 0.0024）和E（P = 0.0015）显示出统计学显著差异。对于ROI-S，E的敏感性和特异性分别为78.8%和84.3%，E的分别为80.8%和81.4%。结论 对于鉴别乳腺良恶性病变，使用带有E和E的ROI-S比ROI-M具有更好的诊断性能。
