Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Department of Pediatrics, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands.
J Adolesc Health. 2017 Nov;61(5):619-625. doi: 10.1016/j.jadohealth.2017.05.027. Epub 2017 Sep 9.
The purpose of the study was to gain more insight into the attitudes of adolescents using medication for attention-deficit/hyperactivity disorder (ADHD).
A cross-sectional study among adolescents (aged 12-18 years) who filled at least two prescriptions for ADHD medication in the preceding year was conducted. Adolescents were invited to fill in an online questionnaire containing questions on sociodemographics, health status, illness perceptions, medication adherence, and medication beliefs.
We invited 1,200 adolescents of whom 181 adolescents (122 males, mean age 14.2 ± 1.7 years) completed the online questionnaire. They mostly used methylphenidate (n = 167; 92%) as a pharmacological treatment for ADHD. Half of the study population (n = 93; 51%) experienced side effects, such as decreased appetite and sleep problems. Most participants (n = 150; 83%) had an indifferent attitude (perceived low necessity and low concerns) toward their ADHD medication. More than half of the study population (n = 111; 61%) reported to be nonadherent based on the Medication Adherence Report Scale. The highest score of the Brief Illness Perception Questionnaire was on "treatment control," suggesting that adolescents do think their medication is effective, despite their indifferent drug attitude.
Most adolescents using ADHD medication had an indifferent attitude toward their medication and reported low adherence rates. These findings should be taken into account when treating adolescents with ADHD; regular counseling and monitoring of the pharmacological treatment might be useful to optimize treatment.
本研究旨在深入了解使用药物治疗注意缺陷多动障碍(ADHD)的青少年的态度。
对过去一年至少开了两次 ADHD 药物处方的青少年(12-18 岁)进行横断面研究。邀请青少年填写一份在线问卷,内容包括社会人口统计学、健康状况、疾病认知、药物依从性和药物信念。
我们邀请了 1200 名青少年,其中 181 名青少年(122 名男性,平均年龄 14.2±1.7 岁)完成了在线问卷。他们主要使用哌甲酯(n=167;92%)作为 ADHD 的药物治疗。半数研究人群(n=93;51%)经历了副作用,如食欲减退和睡眠问题。大多数参与者(n=150;83%)对他们的 ADHD 药物持漠不关心的态度(感知到低必要性和低关注度)。超过一半的研究人群(n=111;61%)根据《药物依从性报告量表》报告存在不依从。《Brief Illness Perception Questionnaire》的最高得分为“治疗控制”,表明尽管青少年对药物的态度漠不关心,但他们确实认为药物有效。
大多数使用 ADHD 药物的青少年对他们的药物持漠不关心的态度,并报告低依从率。在治疗 ADHD 青少年时应考虑到这些发现;定期咨询和监测药物治疗可能有助于优化治疗。