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杀线虫苏云金芽孢杆菌 MYBT18247 的全基因组序列。

Complete genome sequence of the nematicidal Bacillus thuringiensis MYBT18247.

机构信息

Department of Genomic and Applied Microbiology & Göttingen Genomics Laboratory, Institute of Microbiology and Genetics, University of Goettingen, Germany.

Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.

出版信息

J Biotechnol. 2017 Oct 20;260:48-52. doi: 10.1016/j.jbiotec.2017.09.003. Epub 2017 Sep 9.

Abstract

The Gram-positive spore forming bacterium Bacillus thuringiensis MYBT18247 encodes three cry toxin genes, (cry6Ba2, cry6Ba3 and cry21-like) which are active against nematodes. For a better understanding of the evolution of virulence and cry toxins, we present here the complete genome sequence of Bacillus thuringiensis MYBT18247. Various additional virulence factors such as bacteriocins, proteases and hemolysins were identified. In addition, the methylome and the metabolic potential of the strain were analyzed and the strain phylogenetically classified.

摘要

苏云金芽胞杆菌 MYBT18247 编码三种 cry 毒素基因(cry6Ba2、cry6Ba3 和 cry21 样),对线虫具有活性。为了更好地了解毒力和 cry 毒素的进化,我们在此介绍苏云金芽胞杆菌 MYBT18247 的完整基因组序列。鉴定了各种额外的毒力因子,如细菌素、蛋白酶和溶菌酶。此外,还分析了该菌株的甲基组和代谢潜能,并对该菌株进行了系统发育分类。

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