分子内 Pd 催化的糖基羧酰胺的端基 C(sp)-H 活化
Intramolecular Pd-Catalyzed Anomeric C(sp)-H Activation of Glycosyl Carboxamides.
机构信息
BioCIS, Univ Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry, France.
Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Univ Paris-Sud, Université Paris-Saclay , 1, av de la Terrasse, 91198 Gif-sur-Yvette, France.
出版信息
Org Lett. 2017 Oct 6;19(19):5038-5041. doi: 10.1021/acs.orglett.7b02170. Epub 2017 Sep 13.
An expedient method for the synthesis of fused glycosylquinolin-2-ones and glycosylspirooxindoles through an unprecedented intramolecular Pd-catalyzed anomeric C-H activation of the sugar moiety of 2-bromophenyl glycosylcarboxamides is reported. The scope of the reaction is broad and tolerates a wide range of functional groups.
本文报道了一种通过钯催化 2-溴苯甲酰基氨基葡萄糖酰胺糖部分的前所未有的分子内糖位 C-H 活化来合成稠合糖基喹啉-2-酮和糖基螺[吲哚啉-2,3'-吡咯]的简便方法。该反应具有广泛的适用范围，能够容忍多种官能团。
Zotero 插件