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慢性肝病和胆汁淤积患者的血清胆汁酸及常规肝功能检查

Serum bile acids and rountine liver function tests in patients with chronic liver disease and cholestasis.

作者信息

Collins D M, Tongeren A V, Cook H B, Campbell C B

出版信息

N Z Med J. 1979 Jun 13;89(637):432-4.

PMID:289016
Abstract

Serum bile acids were measured in 28 patients with established liver disease. The peak serum level after a meal was as sensitive an index of liver disease as a combination of serum bilirubin, aspartate amino transferase, alkaline phosphatase and gamma glutamyl transpeptidase and was more often abnormal than any one of the four tests. Serum bile acid measurements may be of most value in detecting cirrhosis when the activity of disease is minimal.

摘要

对28例确诊肝病患者的血清胆汁酸进行了检测。餐后血清峰值水平作为肝病指标与血清胆红素、天冬氨酸转氨酶、碱性磷酸酶及γ-谷氨酰转肽酶联合检测一样敏感,且比四项检测中的任何一项更常出现异常。当疾病活动度最低时,血清胆汁酸检测在肝硬化检测中可能最具价值。

相似文献

1
Serum bile acids and rountine liver function tests in patients with chronic liver disease and cholestasis.慢性肝病和胆汁淤积患者的血清胆汁酸及常规肝功能检查
N Z Med J. 1979 Jun 13;89(637):432-4.
2
[Conjugated serum bile acids in chronic liver diseases and cholestasis].[慢性肝病和胆汁淤积中的结合型血清胆汁酸]
Acta Hepatosplenol. 1971 Jul-Aug;18(4):273-86.
3
[Diagnostic value of serum bile acids in chronic diseases of the liver].血清胆汁酸在肝脏慢性疾病中的诊断价值
Med Chir Dig. 1980;9(2):95-7.
4
[Bile acids in the serum of patients with extrahepatic cholestasis with chronic liver diseases].[慢性肝病合并肝外胆汁淤积患者血清中的胆汁酸]
Z Gastroenterol. 1973 May;11(4):279-88.
5
Serum gamma-glutamyl transpeptidase: its clinical significance.血清γ-谷氨酰转肽酶:其临床意义
Acta Med Acad Sci Hung. 1976;33(4):309-19.
6
[Bile acids in chronic hepatopathies].[慢性肝病中的胆汁酸]
Minerva Med. 1986 Dec 22;77(49-50):2287-92.
7
[Diagnostic significance of serum bile acids].[血清胆汁酸的诊断意义]
Schweiz Med Wochenschr. 1975 Apr 26;105(17):533-5.
8
Conjugated and unconjugated serum bile acid levels n patients with hepatobiliary diseases.肝胆疾病患者血清结合及非结合胆汁酸水平
Gastroenterology. 1969 Jun;56(6):1033-9.
9
Clinical significance of fasting serum bile acid in the long-term observation of chronic liver disease.空腹血清胆汁酸在慢性肝病长期观察中的临床意义
Am J Gastroenterol. 1985 Feb;80(2):136-8.
10
[Determination of serum bile acids in hepatobiliary diseases. Clinical applicability].[肝胆疾病中血清胆汁酸的测定。临床应用]
Minerva Med. 1984 Jan 28;75(3-4):99-107.

引用本文的文献

1
Radioimmunoassay of serum glycocholic acid, standard laboratory tests of liver function and liver biopsy findings: comparative study of children with liver disease.血清甘胆酸的放射免疫测定、肝功能标准实验室检查及肝活检结果:肝病患儿的比较研究
J Clin Pathol. 1982 Sep;35(9):1011-7. doi: 10.1136/jcp.35.9.1011.