Hagag Adel A, Erfan Adel A, Elrifaey Shaymaa M, Gamal Rasha M, Harakan Ahmed I
Pediatrics Department, Faculty of Medicine, Tanta University, Gharbia, Egypt.
Endocr Metab Immune Disord Drug Targets. 2017 Nov 16;17(4):309-316. doi: 10.2174/1871530317666170912152351.
Universal reference values of penile length, circumferences and testicular volume in newborns and infants are inappropriate to be used in variable ethnic backgrounds.
The aim of this prospective study was to establish normal reference values for stretched penile length, penile circumference and testicular volume for Egyptian newborn and infants.
This observational cross-sectional study included 1850 healthy male full term newborn and infants applied for routine check-up, aged 0 -24 months, the newborn and infants were recruited from Tanta University Hospital in the period from July 2015 to January 2017. Penile length, penile circumference, testicular volume, weight, length and occipito-frontal circumference were measured.
The studied infants were divided into five groups. Group I: 1-4 weeks, the mean penile length was 3.51 ± 0.49 cm, penile circumference was 3.95 ± 0.48 cm, and testicular size was (right 1.81 ± 0.44 cm and left 1.67 ± 0.47 cm). Group II: > 1-6 months age, the mean penile length was 3.99 ± 0.46 cm, penile circumference was 4.10 ± 0.38 cm, and testicular size was (right 2.10 ± 0.33 cm and left 2.04 ± 0.27 cm). Group III: >6-12 months age, the mean penile length was 4.45 ± 0.48 cm, penile circumference was 4.21 ± 0.33 cm, and testicular size was (right 2.13 ± 0.33 cm and left 2.06 ± 0.28 cm). Group IV: >12-18 months age, the mean penile length was 4.55 ± 0.54 cm, penile circumference was 4.28 ± 0.32 cm, and testicular size was (right 2.12 ± 0.33 cm and left 2.09 ± 0.32 cm). Group V: >18-24 months age, the mean penile length was 4.89 ± 0.63 cm, penile circumference was 4.45 ± 0.33 cm, and testicular size was (right 2.28 ± 0.45 cm and left 2.25 ± 0.45 cm). There were significant positive correlations between penile length, penile circumference, left and right testicular volumes with each other and also with all other anthropometric measures including: weight, height and head circumference.
The age-related values of penile and testicular measurements must be known to be able to determine the abnormal sizes and to monitor treatment of underlying diseases. Our study is a step to achieve accurate reference values of penile and testicular measurements for Egyptian male newborns and infants. Therefore multicenter studies are recommended to establish Egyptian norms.
新生儿和婴儿阴茎长度、周长及睾丸体积的通用参考值不适用于不同种族背景。
本前瞻性研究旨在建立埃及新生儿和婴儿阴茎拉伸长度、阴茎周长及睾丸体积的正常参考值。
本观察性横断面研究纳入1850例健康足月男性新生儿和婴儿，年龄0 - 24个月，于2015年7月至2017年1月期间从坦塔大学医院招募，进行常规检查。测量阴茎长度、阴茎周长、睾丸体积、体重、身长及枕额周长。
研究对象分为五组。第一组：1 - 4周，平均阴茎长度为3.51±0.49cm，阴茎周长为3.95±0.48cm，睾丸大小（右侧1.81±0.44cm，左侧1.67±0.47cm）。第二组：＞1 - 6个月龄，平均阴茎长度为3.99±0.46cm，阴茎周长为4.10±0.38cm，睾丸大小（右侧2.10±0.33cm，左侧2.04±0.27cm）。第三组：＞6 - 12个月龄，平均阴茎长度为4.45±0.48cm，阴茎周长为4.21±0.33cm，睾丸大小（右侧2.13±0.33cm，左侧2.06±0.28cm）。第四组：＞12 - 18个月龄，平均阴茎长度为4.55±0.54cm，阴茎周长为4.28±0.32cm，睾丸大小（右侧2.12±0.33cm，左侧2.09±0.32cm）。第五组：＞18 - 24个月龄，平均阴茎长度为4.89±0.63cm，阴茎周长为4.45±0.33cm，睾丸大小（右侧2.28±0.45cm，左侧2.25±0.45cm）。阴茎长度、阴茎周长、左右睾丸体积之间以及与所有其他人体测量指标（包括体重、身高和头围）之间均存在显著正相关。
必须了解阴茎和睾丸测量的年龄相关值，以便能够确定异常大小并监测基础疾病的治疗。我们的研究是实现埃及男性新生儿和婴儿阴茎及睾丸测量准确参考值的第一步。因此，建议进行多中心研究以建立埃及规范。
