Semiz Serap, Küçüktaşçi Kazim, Zencir Mehmet, Sevinç Ozgür
Division of Pediatric Endocrinology, Pamukkale University Faculty of Medicine, Denizli, Turkey.
Turk J Pediatr. 2011 Nov-Dec;53(6):661-5.
Penile length, penile diameter and testicular volume at birth reflect the activity and normality of the hypothalamus-pituitary-testicular axis. In this prospective longitudinal study, we aimed to measure penis and testicular size in healthy newborns at birth and 6 and 12 months of age. Seven hundred forty-six term healthy male newborns were enrolled in the study. According to measurements taken within 48 hours after birth, mean penile length (MPL) was 2.81 +/- 0.32 cm, mean penile diameter (MPD) 1.04 +/- 0.09 cm, right testicular volume (TV) 1.73 +/- 0.45 ml, and left TV 1.64 +/- 0.48 ml. At 6 months of age, MPL was 3.67 +/- 0.35 cm, MPD 1.23 +/- 0.08 cm, right TV 2.07 +/- 0.31 ml, and left TV 2.00 +/- 0.27 ml. At 12 months of age, MPL was 4.47 +/- 0.43 cm, MPD 1.25 +/- 0.09 cm, right TV 2.01 +/- 0.12 ml, and left TV 2.01 +/- 0.13 ml. There was a weak albeit statistically significant correlation between weight, length and PL at birth. In conclusion, the MPL of newborns was shorter than that reported in the published data from other populations. This situation may be related to ethnicity in addition to the lower birth weight and length of our subjects when compared to the newborns in other populations. We observed a significant increase, more marked during the first six months, in MPL, MPD and TV, which can be explained by the hormonal mechanism during minipuberty.
出生时阴茎长度、阴茎直径和睾丸体积反映了下丘脑 - 垂体 - 睾丸轴的活性和正常状态。在这项前瞻性纵向研究中，我们旨在测量健康新生儿出生时、6个月和12个月大时的阴茎和睾丸大小。746名足月健康男婴纳入了本研究。根据出生后48小时内的测量结果，平均阴茎长度（MPL）为2.81±0.32厘米，平均阴茎直径（MPD）为1.04±0.09厘米，右侧睾丸体积（TV）为1.73±0.45毫升，左侧TV为1.64±0.48毫升。在6个月大时，MPL为3.67±0.35厘米，MPD为1.23±0.08厘米，右侧TV为2.07±0.31毫升，左侧TV为2.00±0.27毫升。在12个月大时，MPL为4.47±0.43厘米，MPD为1.25±0.09厘米，右侧TV为2.01±0.12毫升，左侧TV为2.01±0.13毫升。出生时体重、身长与阴茎长度之间存在微弱但具有统计学意义的相关性。总之，新生儿的MPL低于其他人群已发表数据中报道的数值。与其他人群的新生儿相比，除了我们研究对象出生体重和身长较低外，这种情况可能还与种族有关。我们观察到MPL、MPD和TV显著增加，在前六个月更为明显，这可以用小青春期的激素机制来解释。
