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一名艾滋病患者口腔出现罕见的杆菌性血管瘤病,无皮肤病变伴随——病例报告及文献复习

An unusual case of bacillary angiomatosis in the oral cavity of an AIDS patient who had no concomitant tegumentary lesions - case report and review.

作者信息

Eyer-Silva Walter de Araujo, Soares Pedro Eugênio Mendes Arena, Azevedo Marcelo Costa Velho Mendes de, Silva Guilherme Almeida Rosa da, Signorini Dario José Hart Pontes, Neves-Motta Rogerio, Pinto Jorge Francisco da Cunha, Moura Lívia Machado, Basílio-de-Oliveira Rodrigo Panno, Araujo Luciana Ferreira de, Favacho Alexsandra Rodrigues de Mendonça, Lemos Elba Regina Sampaio

机构信息

Universidade Federal do Estado do Rio de Janeiro, Hospital Universitário Gaffrée e Guinle, Centro de Ciências Biológicas e da Saúde, Rio de Janeiro, Rio de Janeiro, Brazil.

Fundação Oswaldo Cruz, Instituto Oswaldo Cruz, Laboratório de Hantaviroses e Rickettsioses, Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Rev Inst Med Trop Sao Paulo. 2017 Aug 24;59:e59. doi: 10.1590/S1678-9946201759059.

DOI:10.1590/S1678-9946201759059
PMID:28902296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5574626/
Abstract

Bacillary angiomatosis (BA) is an angioproliferative disease of immunocompromised patients that usually presents as vascular tumors in the skin and subcutaneous tissues. It is caused by chronic infections with either Bartonella henselae or B. quintana. Oral cavity BA is exceedingly rare and even rarer without simultaneous cutaneous disease. We report herein the case of a 51-year-old HIV-infected man who presented severe odynophagia and an eroded lesion on the hard palate that progressed to an oronasal fistula. No cutaneous lesions were recorded. Doxycycline led to complete resolution. To the best of our knowledge, only six previous cases of oral BA without tegumentary disease have been previously reported and none of them progressed to fistula.

摘要

杆菌性血管瘤病(BA)是免疫功能低下患者的一种血管增生性疾病,通常表现为皮肤和皮下组织的血管肿瘤。它由汉赛巴尔通体或五日热巴尔通体的慢性感染引起。口腔BA极为罕见,若无同时存在的皮肤疾病则更为罕见。我们在此报告一例51岁的HIV感染男性,该患者出现严重吞咽痛以及硬腭糜烂性病变,病变进展为口鼻瘘。未记录到皮肤病变。强力霉素治疗后病变完全消退。据我们所知,此前仅报告过6例无皮肤疾病的口腔BA病例,且均未进展为瘘管。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9439/5574626/b92390eaf434/1678-9946-rimtsp-S1678-9946201759059-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9439/5574626/a50b7f0f4cc3/1678-9946-rimtsp-S1678-9946201759059-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9439/5574626/b92390eaf434/1678-9946-rimtsp-S1678-9946201759059-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9439/5574626/a50b7f0f4cc3/1678-9946-rimtsp-S1678-9946201759059-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9439/5574626/b92390eaf434/1678-9946-rimtsp-S1678-9946201759059-gf02.jpg

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本文引用的文献

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Bartonella henselae infections in solid organ transplant recipients: report of 5 cases and review of the literature.实体器官移植受者中的亨氏巴尔通体感染:5例报告及文献复习
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