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儿童钝性胰腺创伤的手术治疗与非手术治疗:一项系统评价

Operative Versus Nonoperative Management of Blunt Pancreatic Trauma in Children: A Systematic Review.

作者信息

Koh Ezra Y, van Poll Daan, Goslings J Carel, Busch Olivier R, Rauws Erik A, Oomen Matthijs W, Besselink Marc G

机构信息

From the *Department of Pediatric Surgery, Emma Children's Hospital, and Departments of †Surgery, ‡Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

Pancreas. 2017 Oct;46(9):1091-1097. doi: 10.1097/MPA.0000000000000916.

Abstract

The aim of this study was to compare operative versus nonoperative management of blunt pancreatic trauma in children. A systematic literature search was performed. Studies including children with blunt pancreatic injuries classified according to the American Association for the Surgery of Trauma classification were included. The primary outcome was pseudocyst formation. After screening 526 studies, 23 studies with 928 patients were included. Sufficient data were available for 674 patients (73%). Of 309 patients with grade I or II injuries, 258 (83%) were initially managed nonoperatively with a 96% success rate. Of 365 patients with grade III, IV, or V injuries, nonoperative management was initially chosen for 167 patients (46%) with an 89% success rate. Pseudocysts occurred in 18% of patients managed nonoperatively versus 4% of patients managed operatively (P < 0.01), of whom 65% were treated nonoperatively. Hospitalization was 20.5 days after nonoperative versus 15.1 days after operative management (nonparametric t test, P = 0.41). Blunt pancreatic trauma in children can be managed nonoperatively in the majority of patients with grade I or II injuries and in about half of the patients with grade III to V injuries. Although pseudocysts are more common after nonoperative management, two thirds can be managed nonoperatively.

摘要

本研究的目的是比较儿童钝性胰腺创伤的手术治疗与非手术治疗。进行了系统的文献检索。纳入了根据美国创伤外科协会分类法对钝性胰腺损伤儿童进行分类的研究。主要结局是假性囊肿形成。在筛选了526项研究后,纳入了23项研究中的928例患者。674例患者(73%)有足够的数据。在309例I级或II级损伤患者中,258例(83%)最初采用非手术治疗,成功率为96%。在365例III级、IV级或V级损伤患者中,167例(46%)最初选择非手术治疗,成功率为89%。非手术治疗的患者中有18%发生假性囊肿,而手术治疗的患者中为4%(P<0.01),其中65%接受非手术治疗。非手术治疗后的住院时间为20.5天,而手术治疗后为15.1天(非参数t检验,P = 0.41)。大多数I级或II级损伤的儿童钝性胰腺创伤患者以及约一半III级至V级损伤的患者可以采用非手术治疗。虽然非手术治疗后假性囊肿更常见,但三分之二可以采用非手术治疗。

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