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加纳北部地区2010 - 2015年细菌性脑膜炎监测数据评估

Evaluation of bacterial meningitis surveillance data of the northern region, Ghana, 2010-2015.

作者信息

Kaburi Basil Benduri, Kubio Chrysantus, Kenu Ernest, Ameme Donne Kofi, Mahama Jacob Yakubu, Sackey Samuel Oko, Afari Edwin Andrew

机构信息

Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, College of Health Sciences, University of Ghana, Legon.

Ghana Health Service, West Gonja District Health Directorate, Damongo, Ghana.

出版信息

Pan Afr Med J. 2017 Jun 30;27:164. doi: 10.11604/pamj.2017.27.164.11036. eCollection 2017.

Abstract

INTRODUCTION

Bacterial meningitis is a disease of major public health importance especially for countries such as Ghana; whose northern part lies within the meningitis belt. The Northern region of Ghana has been recording cases with outbreaks over the years. In order to generate evidence to improve surveillance, we described the epidemiology of bacterial meningitis using surveillance data of the northern region.

METHODS

Bacterial meningitis datasets from January 2010 to December 2015 for all the 26 districts of the Northern region were retrieved from line lists. Data were analyzed in terms of person, place, time, and identity of causative organisms using descriptive statistics. The results were presented as proportions, rates, tables and graphs.

RESULTS

A total of 1,176 cases were reported. Of these, 53.5% (629/1,176) were males. The proportion of cases aged 0 to 29 years was 77.4%. The Overall Case Fatality Rate (CFR) was 9.7% (114/1,176). About 65% of all cases were recorded from January to April. Only 23.7% (279/1,176) of cases were laboratory-confirmed. and accounted for 91.4% of confirmed cases. Over the period, the incidence reduced from 9.0/100,000 population to 3.8/100,000 population and CFR reduced from 16.6% to 5.7%.

CONCLUSION

Most cases of bacterial meningitis were recorded in the dry season and in persons younger than 30 years. Less than a quarter of cases were laboratory confirmed, and no new bacteria species were identified. Both morbidity and mortality rates were on the decline. There is the need to consolidate these gains by intensifying meningitis surveillance and improving on the rate of laboratory case confirmation.

摘要

引言

细菌性脑膜炎是一种对公共卫生具有重大意义的疾病,对于加纳这样的国家尤为如此;该国北部位于脑膜炎带内。加纳北部地区多年来一直记录有病例爆发情况。为了生成改进监测的证据,我们利用北部地区的监测数据描述了细菌性脑膜炎的流行病学情况。

方法

从一览表中检索了2010年1月至2015年12月加纳北部地区所有26个区的细菌性脑膜炎数据集。使用描述性统计方法,从人、地点、时间和致病生物体的身份方面对数据进行了分析。结果以比例、率、表格和图表的形式呈现。

结果

共报告了1176例病例。其中,53.5%(629/1176)为男性。0至29岁病例的比例为77.4%。总体病死率(CFR)为9.7%(114/1176)。约65%的病例是在1月至4月记录的。只有23.7%(279/1176)的病例得到实验室确诊。 和 占确诊病例的91.4%。在此期间,发病率从每10万人口9.0例降至每10万人口3.8例,病死率从16.6%降至5.7%。

结论

大多数细菌性脑膜炎病例记录于旱季和30岁以下人群。不到四分之一的病例得到实验室确诊,且未发现新的细菌种类。发病率和死亡率均呈下降趋势。有必要通过加强脑膜炎监测和提高实验室病例确诊率来巩固这些成果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b56/5567946/dfc550722a80/PAMJ-27-164-g001.jpg

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