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胱抑素SN通过自噬诱导和经由谷胱甘肽还原酶活性调节活性氧来抑制金诺芬诱导的结直肠癌细胞死亡。

Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer.

作者信息

Oh Byung Moo, Lee Seon-Jin, Cho Hee Jun, Park Yun Sun, Kim Jong-Tae, Yoon Suk Ran, Lee Sang Chul, Lim Jong-Seok, Kim Bo-Yeon, Choe Yong-Kyung, Lee Hee Gu

出版信息

Cell Death Dis. 2017 Sep 14;8(9):e3053. doi: 10.1038/cddis.2017.446.

DOI:10.1038/cddis.2017.446
PMID:28906491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5636990/
Abstract

This corrects the article DOI: 10.1038/cddis.2017.100.

摘要

本文更正了文章的数字对象标识符(DOI):10.1038/cddis.2017.100。

相似文献

1
Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer.胱抑素SN通过自噬诱导和经由谷胱甘肽还原酶活性调节活性氧来抑制金诺芬诱导的结直肠癌细胞死亡。
Cell Death Dis. 2017 Sep 14;8(9):e3053. doi: 10.1038/cddis.2017.446.
2
Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer.胱抑素SN通过自噬诱导和经由谷胱甘肽还原酶活性调节活性氧来抑制金诺芬诱导的结直肠癌细胞死亡。
Cell Death Dis. 2017 Mar 16;8(3):e2682. doi: 10.1038/cddis.2017.100.
3
Auranofin induces mesothelioma cell death through oxidative stress and GSH depletion.金诺芬通过氧化应激和谷胱甘肽耗竭诱导间皮瘤细胞死亡。
Oncol Rep. 2016 Jan;35(1):546-51. doi: 10.3892/or.2015.4382. Epub 2015 Nov 2.
4
Auranofin, an inhibitor of thioredoxin reductase, induces apoptosis in hepatocellular carcinoma Hep3B cells by generation of reactive oxygen species.金诺芬,一种硫氧还蛋白还原酶抑制剂,通过产生活性氧诱导肝癌Hep3B细胞凋亡。
Gen Physiol Biophys. 2017 Apr;36(2):117-128. doi: 10.4149/gpb_2016043. Epub 2017 Feb 20.
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Differential redox sensitivity of cathepsin B and L holds the key to autophagy-apoptosis interplay after Thioredoxin reductase inhibition in nutritionally stressed SH-SY5Y cells.组织蛋白酶B和L的不同氧化还原敏感性是营养应激的SH-SY5Y细胞中硫氧还蛋白还原酶抑制后自噬-凋亡相互作用的关键。
Free Radic Biol Med. 2017 Jul;108:819-831. doi: 10.1016/j.freeradbiomed.2017.05.005. Epub 2017 May 3.
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Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion.金诺芬通过氧化应激和谷胱甘肽耗竭诱导HeLa细胞凋亡和坏死。
Mol Med Rep. 2015 Feb;11(2):1428-34. doi: 10.3892/mmr.2014.2830. Epub 2014 Oct 31.
7
Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer.激肽释放酶相关肽酶6通过激活自噬减弱金诺芬诱导的胃癌细胞死亡,从而诱导化疗耐药。
Oncotarget. 2016 Dec 20;7(51):85332-85348. doi: 10.18632/oncotarget.13352.
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Identification of Cystatin SN as a novel tumor marker for colorectal cancer.鉴定胱抑素SN作为结直肠癌的一种新型肿瘤标志物。
Int J Oncol. 2009 Jul;35(1):33-40.
9
Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation.金诺芬对内源性抗氧化剂的选择性抑制会导致线粒体氧化应激,而补充硒可以对抗这种应激。
Biochem Pharmacol. 2017 Dec 15;146:42-52. doi: 10.1016/j.bcp.2017.09.009. Epub 2017 Sep 22.
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Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species.金诺芬通过靶向硫氧还蛋白还原酶并导致活性氧的过量产生来使肿瘤细胞对放疗敏感。
Oncotarget. 2017 May 30;8(22):35728-35742. doi: 10.18632/oncotarget.16113.

引用本文的文献

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Discov Oncol. 2025 Mar 8;16(1):282. doi: 10.1007/s12672-025-02026-z.
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Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation.单核细胞向巨噬细胞分化以及细胞氧化还原稳态的改变促进了细胞类型特异性的 HIV 潜伏再激活。
Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2313823121. doi: 10.1073/pnas.2313823121. Epub 2024 Apr 29.
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miRNA-6715-5p Inhibits Cellular Proliferation and Invasion in Colorectal Cancer by Directly Targeting CST4.微小RNA-6715-5p通过直接靶向CST4抑制结直肠癌的细胞增殖和侵袭。
J Oncol. 2021 May 29;2021:7615712. doi: 10.1155/2021/7615712. eCollection 2021.
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Licochalcone a Induces ROS-Mediated Apoptosis through TrxR1 Inactivation in Colorectal Cancer Cells.甘草查尔酮 A 通过抑制硫氧还蛋白还原酶 1 诱导结直肠癌细胞发生活性氧介导的凋亡。
Biomed Res Int. 2020 May 27;2020:5875074. doi: 10.1155/2020/5875074. eCollection 2020.
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Cystatin SN Affects Cell Proliferation by Regulating the ERα/PI3K/AKT/ERα Loopback Pathway in Breast Cancer.胱抑素SN通过调节乳腺癌中的ERα/PI3K/AKT/ERα反馈通路影响细胞增殖。
Onco Targets Ther. 2019 Dec 23;12:11359-11369. doi: 10.2147/OTT.S234328. eCollection 2019.
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The binding landscape of a partially-selective isopeptidase inhibitor with potent pro-death activity, based on the bis(arylidene)cyclohexanone scaffold.基于双(芳亚甲基)环己酮骨架的具有强促死亡活性的部分选择性异肽酶抑制剂的结合景观。
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