Division of General Internal Medicine.
University Hospital of South Manchester, University of Manchester, Manchester Academic Health Science Centre, United Kingdom.
J Infect Dis. 2017 Aug 15;216(suppl_3):S484-S492. doi: 10.1093/infdis/jix103.
Improved understanding of basic mycological, pharmacological, and immunological processes has led to important advances in the diagnosis and treatment of invasive fungal infections. However, the rise of fungi that are resistant to existing antifungal agents poses a substantial threat to human health. Addressing this expanding problem is an urgent priority for the international research community. In this article, we highlight important diagnostic and therapeutic advances that address the rise of resistant fungi as well as new public health initiatives that warrant further investigation to help curb the spread of these potentially lethal organisms.
对基础真菌学、药理学和免疫学过程的深入了解，推动了侵袭性真菌感染的诊断和治疗方面的重要进展。然而，现有抗真菌药物耐药真菌的出现，对人类健康构成了重大威胁。解决这一日益严重的问题，是国际研究界的当务之急。本文重点介绍了一些重要的诊断和治疗进展，这些进展针对耐药真菌的出现，以及一些新的公共卫生措施，这些措施值得进一步研究，以帮助遏制这些潜在致命生物的传播。
