肉瘤样肾细胞癌：苹果不落在树之外。
Sarcomatoid Renal Cell Carcinoma: The Apple Doesn't Fall Far from the Tree.
机构信息
Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California.
Department of Internal Medicine, Division of Medical Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.
出版信息
Clin Cancer Res. 2017 Nov 1;23(21):6381-6383. doi: 10.1158/1078-0432.CCR-17-2039. Epub 2017 Sep 14.
The most comprehensive sequencing effort of sarcomatoid renal cell carcinoma (sRCC) to date reinforces the notion that the sarcomatoid component is closely related to the epithelial component of the cancer. This work also challenges the notion that sRCC evolves from low-grade RCC and identifies potential mediators of sarcomatoid differentiation. .
迄今为止，对肉瘤样肾细胞癌（sRCC）进行的最全面测序工作证实了肉瘤样成分与癌症的上皮成分密切相关的观点。这项工作还挑战了 sRCC 从低级别 RCC 进化而来的观点，并确定了肉瘤样分化的潜在介质。
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