Bråbäck Martin, Ekström Lars, Troberg Katja, Nilsson Suzan, Isendahl Pernilla, Brådvik Louise, Håkansson Anders
Addiction Center Malmö, Division of Psychiatry, Malmö, Sweden.
Faculty of Medicine, Department of Clinical Sciences, Psychiatry, Lund University, Lund, Sweden.
Front Psychiatry. 2017 Aug 31;8:161. doi: 10.3389/fpsyt.2017.00161. eCollection 2017.
Heroin dependence is associated with high mortality. Opioid agonist treatment (OAT) with methadone or buprenorphine has strong evidence for treatment of this relapsing condition. In our setting, OAT has been associated with strict and demanding intake procedures, often with requirements of social stability, but also high, approximately 80 percent 12-month retention rates. In a recent randomized controlled trial, we demonstrated high rates of successful rapid referral from a syringe exchange programme (SEP) to treatment with methadone or buprenorphine, including actual treatment initiation. The objectives of this study were to assess 12-month retention rates, in order to assess whether a novel referral program of current drug users at a SEP would achieve retention rates comparable to more traditional intake procedures.
The present report is a 12-month follow-up of 71 patients who successfully started treatment with methadone or buprenorphine/naloxone. Patient data from baseline and at 12 months were collected.
Out of the 71 patients who started treatment, 58 (82%) were still in treatment after 12 months.
This was a population, referred from a SEP, with a high drug use severity on admission and no pretreatment requirement for social stability, but there were still high retention rates at 12 months comparable to regular opioid agonist clinics in our setting.
海洛因依赖与高死亡率相关。美沙酮或丁丙诺啡的阿片类激动剂治疗(OAT)有充分证据可用于治疗这种复发性疾病。在我们的环境中,OAT与严格且要求苛刻的服药程序相关,通常有社会稳定方面的要求,但12个月的留存率也很高,约为80%。在最近一项随机对照试验中,我们证明了从注射器交换计划(SEP)成功快速转介到美沙酮或丁丙诺啡治疗(包括实际开始治疗)的比例很高。本研究的目的是评估12个月的留存率,以评估SEP中当前吸毒者的新型转介计划是否能实现与更传统的服药程序相当的留存率。
本报告是对71名成功开始美沙酮或丁丙诺啡/纳洛酮治疗的患者进行的12个月随访。收集了患者基线和12个月时的数据。
在开始治疗的71名患者中,58名(82%)在12个月后仍在接受治疗。
这是一组从SEP转介来的患者,入院时吸毒严重程度高,且对社会稳定无预处理要求,但12个月时的留存率仍然很高,与我们环境中的常规阿片类激动剂诊所相当。