Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Lung. 2017 Dec;195(6):693-698. doi: 10.1007/s00408-017-0049-7. Epub 2017 Sep 15.
This study aims to determine the impact of physical activity on asthma symptom reporting among children living in an inner city. Among 147 children aged 5-12 years with physician-diagnosed asthma, we assessed asthma symptoms using twice-daily diaries and physical activity using the physical activity questionnaire for children during three 8-day periods (baseline, 3 and 6 months). Linear, logistic, and quasi-poisson regression models were used to determine the association between physical activity and asthma symptoms; adjusting for age, sex, race, BMI, caregiver's education, asthma severity, medication use, and season. A 1-unit increase in PAQ score was significantly associated with reporting more nocturnal symptoms [risk ratio (RR): 1.03; 95% CI 1.00-1.06], daytime symptoms (RR: 1.04; 95% CI 1.00-1.09), being bothered by asthma (RR: 1.05; 95% CI 1.00-1.09), and trouble breathing (RR: 1.05; 95% CI 1.00-1.10). Level of physical activity should be taken into account in clinical management of asthma and epidemiological studies of asthma symptom burden.
本研究旨在确定体力活动对居住在市中心的儿童哮喘症状报告的影响。在 147 名年龄在 5-12 岁、经医生诊断患有哮喘的儿童中，我们使用每日两次的日记评估哮喘症状，并在三个 8 天期间（基线、3 个月和 6 个月）使用儿童体力活动问卷评估体力活动。使用线性、逻辑和拟泊松回归模型来确定体力活动与哮喘症状之间的关联；调整年龄、性别、种族、BMI、照顾者教育程度、哮喘严重程度、药物使用和季节。PAQ 评分增加 1 个单位与报告更多夜间症状（风险比 [RR]：1.03；95%置信区间 [CI]：1.00-1.06）、白天症状（RR：1.04；95% CI：1.00-1.09）、哮喘困扰（RR：1.05；95% CI：1.00-1.09）和呼吸困难（RR：1.05；95% CI：1.00-1.10）显著相关。在哮喘的临床管理和哮喘症状负担的流行病学研究中，应考虑体力活动水平。
