Rajendran Simon, Jensen Debra, McCluggage W Glenn
Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, United Kingdom (S.R., W.G.M.) Douglass Hanly Moir Pathology, Sydney, New South Wales, Australia (D.J.).
Int J Gynecol Pathol. 2019 Jan;38(1):103-107. doi: 10.1097/PGP.0000000000000455.
The development of a somatic neoplasm within an ovarian dermoid cyst (mature cystic teratoma) is a rare, but well described, phenomenon which occurs in approximately 1% of all cases. Any of the tissue components of a dermoid cyst has the potential to undergo neoplastic transformation with carcinoid tumors and squamous cell carcinomas being among the most common neoplasms. We report a case of a ganglioneuroblastoma arising within an ovarian dermoid cyst, an association which, as far as we are aware, has not been described previously.
卵巢皮样囊肿(成熟囊性畸胎瘤)内发生体细胞肿瘤是一种罕见但已有充分描述的现象,约占所有病例的1%。皮样囊肿的任何组织成分都有可能发生肿瘤转化,类癌肿瘤和鳞状细胞癌是最常见的肿瘤类型。我们报告一例卵巢皮样囊肿内发生神经节神经母细胞瘤的病例,据我们所知,此前尚未有过这种关联的描述。