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成年女性肾上腺节细胞神经母细胞瘤伴肾门附近转移:一例报告并文献复习

Adrenal ganglioneuroblastoma with metastasis near the renal hilum in an adult female: A case report and review of the literature.

作者信息

Zhang Xinzhang, Zhang Yiwen, Peng Dan, Shi Xin, Zhang Zhuorui, Wang Junfeng, Zhang Xue, Leng Jinjun, Li Wei

机构信息

Department of Urology, The Affiliated Hospital of Kunming University of Science and Technology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650100, P.R. China.

Medical School, Kunming University of Science and Technology, Kunming, Yunnan 650500, P.R. China.

出版信息

Oncol Lett. 2024 Feb 29;27(4):187. doi: 10.3892/ol.2024.14319. eCollection 2024 Apr.

DOI:10.3892/ol.2024.14319
PMID:38486945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10938287/
Abstract

Ganglioneuroblastoma (GNB), predominantly observed in children, is an uncommon malignant tumor in adults, with established treatment protocols notably lacking. The present study details the case of a 20-year-old woman who presented with a left adrenal gland mass, identified during a physical examination. Additionally, an unidentified mass was noted near the renal hilum in the preoperative evaluation. Following thorough preoperative preparation, both the primary adrenal gland mass and the renal hilar mass were surgically removed. The procedure concluded successfully. Pathological analysis confirmed that the left adrenal mass was a GNB and identified the renal hilar mass as a metastatic extension. Postoperative examination revealed a new formation at the original surgical site, later verified as a postoperative scar. Through the publication of a case report and extensive literature review, the present study aims to enhance our understanding of this condition, providing valuable diagnostic, therapeutic and post-recovery references for this rare adult disease.

摘要

神经节神经母细胞瘤(GNB)主要见于儿童,在成人中是一种罕见的恶性肿瘤,目前明显缺乏既定的治疗方案。本研究详细介绍了一名20岁女性的病例,该患者在体格检查中发现左肾上腺肿块。此外,术前评估时在肾门附近发现了一个不明肿块。经过充分的术前准备,原发性肾上腺肿块和肾门肿块均通过手术切除。手术成功完成。病理分析证实左肾上腺肿块为GNB,并确定肾门肿块为转移灶。术后检查发现原手术部位有新形成物,后来证实为术后瘢痕。通过发表病例报告和广泛的文献综述,本研究旨在加深我们对这种疾病的理解,为这种罕见的成人疾病提供有价值的诊断、治疗和术后康复参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/a0b12fd4d91c/ol-27-04-14319-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/5a3bd691d1a5/ol-27-04-14319-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/d3852200e3b4/ol-27-04-14319-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/45b947124962/ol-27-04-14319-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/b65f4a8009a9/ol-27-04-14319-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/2f9f84d32b3a/ol-27-04-14319-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/a0b12fd4d91c/ol-27-04-14319-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/5a3bd691d1a5/ol-27-04-14319-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/d3852200e3b4/ol-27-04-14319-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/45b947124962/ol-27-04-14319-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/b65f4a8009a9/ol-27-04-14319-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/2f9f84d32b3a/ol-27-04-14319-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f4/10938287/a0b12fd4d91c/ol-27-04-14319-g05.jpg

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本文引用的文献

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Cureus. 2023 Jan 3;15(1):e33288. doi: 10.7759/cureus.33288. eCollection 2023 Jan.
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Unique case of adult onset posterior mediastinal ganglioneuroblastoma on 68Ga DOTATATE PET/CT.
68Ga DOTATATE PET/CT检查发现的成人期后纵隔神经节神经母细胞瘤罕见病例。
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A rare case of adrenal ganglioneuroblastoma-intermixed in an adult and a review of literature.一例罕见的成人肾上腺节细胞神经母细胞瘤混合型病例及文献复习
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