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比较接受阑尾膀胱造口术的儿童和青少年的住院与门诊肠道准备情况。

Comparing inpatient versus outpatient bowel preparation in children and adolescents undergoing appendicovesicostomy.

作者信息

Weatherly David L, Szymanski Konrad M, Whittam Benjamin M, Bennett William E, King Shelly, Misseri Rosalia, Kaefer Martin, Rink Richard C, Cain Mark P

机构信息

Division of Pediatric Urology, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.

Division of Pediatric Urology, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.

出版信息

J Pediatr Urol. 2018 Feb;14(1):50.e1-50.e6. doi: 10.1016/j.jpurol.2017.07.013. Epub 2017 Aug 26.

Abstract

PURPOSE

The need for mechanical inpatient bowel preparation (IBP) in reconstructive pediatric urology has come under scrutiny, secondary to literature demonstrating little benefit regarding outcomes. Starting in 2013, a majority of patients undergoing reconstructive procedures at our institution no longer underwent IBP. We hypothesized that outpatient bowel preparation (OBP) would reduce length of stay (LOS) without increasing postoperative complications after appendicovesicostomy surgery.

MATERIALS AND METHODS

An institutional database of patients undergoing lower urinary tract reconstruction between May 2010 and December 2014 was reviewed. Starting in 2013, a departmental decision was made to replace IBP with OBP. Patients undergoing an augmentation cystoplasty or continent ileovesicostomy were excluded because of insufficient numbers undergoing OBP. Patients undergoing IBP were admitted 1 day prior to surgery and received polyethylene glycol/electrolyte solution. A personalized preoperative OBP was introduced in 2013. Cost data were obtained from the Pediatric Health Information System.

RESULTS

Sixty-seven patients met the inclusion criteria, with 30 (44.8%) undergoing IBP. There were no differences with respect to gender, age, presence of ventriculoperitoneal shunt, body mass index, glomerular filtration rate, preoperative diagnosis, operative time, and prior or simultaneous associated surgeries (p ≥ 0.07). Patients undergoing an IBP had a longer median LOS (7 vs. 5 days, p = 0.0002) and a higher median cost (US$4,288, p = 0.01). Postoperative complications in both groups were uncommon and were classified as Clavien-Dindo grade 1-2, with no statistical difference (IBP 20.0% vs. OBP 5.4%, p = 0.13). No serious postoperative complication occurred, such as a dehiscence, bowel obstruction, or shunt infection.

DISCUSSION

This is the first analysis of hospitalization costs and IBP, showing a higher median cost of US$4288 compared with OBP. The LOS was shorter with an OBP (figure), similar to a previous report. Similar complication rates between the groups add to the growing body of literature that avoidance of IBP is safe in pediatric lower urinary tract reconstruction. Being a retrospective review of a practice change, differences in care that influenced cost and LOS may be missing. Also, as the surgeons do not know if a usable appendix is initially present, our data may not extrapolate to all patients. Despite these potential limitations, our data support the safety of utilizing OBP in patients with a high likelihood of a usable appendix, including those undergoing a synchronous Malone antegrade continence enema via a split-appendix technique.

CONCLUSION

In patients undergoing an appendicovesicostomy, preoperative IBP led to longer LOS and higher costs of hospitalization. OBP was not associated with increased risks of postoperative complications.

摘要

目的

由于文献表明机械性住院患者肠道准备(IBP)对手术结果益处不大,小儿重建泌尿外科对其需求受到了审视。自2013年起,我院接受重建手术的大多数患者不再进行IBP。我们推测门诊肠道准备(OBP)可缩短阑尾膀胱造瘘术后的住院时间(LOS),且不增加术后并发症。

材料与方法

回顾了2010年5月至2014年12月期间接受下尿路重建患者的机构数据库。自2013年起,科室决定用OBP取代IBP。因接受OBP的患者数量不足,接受膀胱扩大术或可控性回肠膀胱术的患者被排除。接受IBP的患者在手术前1天入院,并接受聚乙二醇/电解质溶液。2013年引入了个性化的术前OBP。成本数据来自儿科健康信息系统。

结果

67例患者符合纳入标准,其中30例(44.8%)接受了IBP。在性别、年龄、是否存在脑室腹腔分流、体重指数、肾小球滤过率、术前诊断、手术时间以及既往或同期相关手术方面,两组间无差异(p≥0.07)。接受IBP的患者中位住院时间更长(7天对5天,p = 0.0002),中位成本更高(4288美元,p = 0.01)。两组术后并发症均不常见,均归类为Clavien-Dindo 1-2级,无统计学差异(IBP为20.0%,OBP为5.4%,p = 0.13)。未发生严重的术后并发症,如裂开、肠梗阻或分流感染。

讨论

这是首次对住院成本和IBP进行的分析,显示与OBP相比,IBP的中位成本更高,为4288美元。OBP组的住院时间更短(见图),与之前的报告相似。两组间相似的并发症发生率进一步支持了越来越多的文献观点,即在小儿下尿路重建中避免IBP是安全的。作为对一种实践改变的回顾性研究,可能遗漏了影响成本和住院时间的护理差异。此外,由于外科医生最初不知道阑尾是否可用,我们的数据可能无法外推至所有患者。尽管存在这些潜在局限性,但我们的数据支持在阑尾可能可用的患者中使用OBP的安全性,包括那些通过劈开阑尾技术同步进行马龙顺行性节制灌肠的患者。

结论

在接受阑尾膀胱造瘘术的患者中,术前IBP导致更长的住院时间和更高的住院成本。OBP与术后并发症风险增加无关。

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