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蛋白质-配体结合有多快?

How Fast Is Protein-Ligand Association?

机构信息

Istituto Pasteur - Fondazione Cenci Bolognetti and Istituto di Biologia e Patologia Molecolari del CNR, Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza University of Rome, 00185 Rome, Italy.

Department of Medical Biochemistry and Microbiology, Uppsala University, BMC Box 582, SE-75123 Uppsala, Sweden.

出版信息

Trends Biochem Sci. 2017 Nov;42(11):847-849. doi: 10.1016/j.tibs.2017.08.007. Epub 2017 Sep 13.

Abstract

There is increasing interest in studying protein interactions and their role in cell biology using kinetics. However, there is confusion about the proper terminology in terms of the distinction between rates and rate constants. We recommend a more stringent use of the words speed, fast, slow, rate, and rate constant.

摘要

人们越来越感兴趣地使用动力学研究蛋白质相互作用及其在细胞生物学中的作用。然而,在区分速率和速率常数方面,术语的使用存在混淆。我们建议更严格地使用速度、快、慢、速率和速率常数这几个词。

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