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一种具有大斯托克斯位移和近红外荧光的独特直线型π-扩展罗丹明染料,用于生物成像。

A unique rectilinearly π-extended rhodamine dye with large Stokes shift and near-infrared fluorescence for bioimaging.

作者信息

Liu Chang, Jiao Xiaojie, Wang Qing, Huang Kun, He Song, Zhao Liancheng, Zeng Xianshun

机构信息

Tianjin Key Laboratory for Photoelectric Materials and Devices, School of Materials Science & Engineering, Tianjin University of Technology, Tianjin 300384, China.

出版信息

Chem Commun (Camb). 2017 Sep 26;53(77):10727-10730. doi: 10.1039/c7cc06220f.

Abstract

The synthesis of a novel rectilinearly π-extended rhodamine dye (TJ730) has been described. It exhibits NIR fluorescence emission with a Stokes shift of >110 nm. TJ730 and its ester derivative are cell permeable, have low cytotoxicity, are biocompatible, and can be directly used as NIR tracers for lysosome staining. Using TJ730 as a precursor, two probes have been prepared for Cu.

摘要

已报道了一种新型直线型π-扩展罗丹明染料(TJ730)的合成。它表现出近红外荧光发射,斯托克斯位移大于110 nm。TJ730及其酯衍生物具有细胞渗透性,细胞毒性低,具有生物相容性,可直接用作溶酶体染色的近红外示踪剂。以TJ730为前体,制备了两种用于检测铜的探针。

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