Nakae Yuri, Horikawa Dai, Tamiya Keiko, Namiki Akiyoshi
Department of Anesthesia, Hokkaido Children's Medical Center, 1-10-1 Zenibako, 047-0261, Otaru, Japan.
Department of Anesthesiology, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, 060-0061, Sapporo, Japan.
J Anesth. 1998 Dec;12(4):175-179. doi: 10.1007/BF02481726.
The aim of this study was to compare the effect of low-flow anesthesia with or without a heat and moisture exchanger with high-flow anesthesia on airway gas humidification in children.
One hundred twenty children were randomly assigned to one of three groups: low-flow anesthesia with 0.5l·min of total gas flow (LFA,n=40), low-flow anesthesia with 0.5l·min using a heat and moisture exchanger (HME,n=40), and high-flow anesthesia with 6l·min (HFA,n=40). The temperature and relative humidity of the inspired gas were measured throughout anesthesia.
The relative humidity of the inspired gas in the HME group was increased compared with that of the LFA and HFA groups 20 min after induction (p<0.05). The airway humidification in the LFA group was higher than that in the HFA group 10 min after induction (p<0.05). The temperature of the inspired gas in the HME group was increased compared with that in the LFA and HFA groups after 70 min (P<0.05).
Low-flow anesthesia is less effective in providing adequate humidification of inspired gas than low-flow anesthesia with a heat and moisture exchanger, but significantly better than high-flow anesthesia in children.
本研究旨在比较采用或不采用热湿交换器的低流量麻醉与高流量麻醉对儿童气道气体湿化的影响。
120名儿童被随机分为三组之一：总气体流量为0.5l·min的低流量麻醉组（LFA，n = 40）、使用热湿交换器且总气体流量为0.5l·min的低流量麻醉组（HME，n = 40）和总气体流量为6l·min的高流量麻醉组（HFA，n = 40）。在整个麻醉过程中测量吸入气体的温度和相对湿度。
诱导20分钟后，HME组吸入气体的相对湿度高于LFA组和HFA组（p < 0.05）。诱导10分钟后，LFA组的气道湿化高于HFA组（p < 0.05）。70分钟后，HME组吸入气体的温度高于LFA组和HFA组（P < 0.05）。
低流量麻醉在为吸入气体提供充分湿化方面不如使用热湿交换器的低流量麻醉有效，但在儿童中明显优于高流量麻醉。
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