Söderlund C
Dept. of Surgery, Södersjukhuset, Stockholm, Sweden.
Scand J Gastroenterol Suppl. 1987;137:50-5. doi: 10.3109/00365528709089762.
Vasopressin has been in clinical use for more than two decades in the treatment of upper gastrointestinal haemorrhage, especially bleeding oesophageal varices. However the haemostatic effect in controlled clinical trials is far from impressive, and no double-blind placebo controlled trial has shown even a trend in favour of vasopressin. These studies, the effects, side-effects, and clinical use of vasopressin and its long-acting analogue triglycylvasopressin, glypressin, are reviewed.
二十多年来，血管加压素一直用于治疗上消化道出血，尤其是食管静脉曲张破裂出血。然而，在对照临床试验中的止血效果远不尽如人意，而且尚无双盲安慰剂对照试验显示血管加压素有任何积极趋势。本文对血管加压素及其长效类似物三甘氨酰赖氨酸加压素（甘氨加压素）的研究、作用、副作用及临床应用进行综述。
