利用DRβ和DQβcDNA探针通过限制性片段长度多态性分析进行基因组HLA分型，结果显示寻常型银屑病患者中DR - DQ存在正常连锁。
Genomic HLA-typing by RFLP-analysis using DR beta and DQ beta cDNA probes reveals normal DR-DQ linkages in patients with psoriasis vulgaris.
作者信息
Olerup O, Wallin J, Carlsson B, Marcusson J, Emtestam L, Björnelius E, Möller E
机构信息
Department of Clinical Immunology, Karolinska Institute at Huddinge Hospital, Sweden.
出版信息
Tissue Antigens. 1987 Sep;30(3):139-42. doi: 10.1111/j.1399-0039.1987.tb01611.x.
Abstract
Thirty-five patients with psoriasis vulgaris were HLA-typed by RFLP-analysis using DR beta and DQ beta cDNA probes. A closer association to the DQ than to the DR locus was not found in this small material.
摘要
采用DRβ和DQβ cDNA探针，通过限制性片段长度多态性分析（RFLP分析）对35例寻常型银屑病患者进行HLA分型。在这个小样本中，未发现与DQ位点的关联比与DR位点的关联更密切。
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