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用于初发复杂冠状动脉病变的新型紫杉醇涂层刻痕球囊——首例报告

Novel paclitaxel-coated scoring ballon for de novo complex coronary lesions-first report.

作者信息

di Palma Gaetano, Cortese Bernardo

机构信息

Interventional Cardiology, ASST Fatebenefratelli-Sacco, Milano, Italy; Division of Cardiology, Cardio-thoracic and Respiratory Sciences Department, Second University of Naples, AO Dei Colli-Monaldi Hospital, Italy.

Interventional Cardiology, ASST Fatebenefratelli-Sacco, Milano, Italy; Fondazione Monasterio CNR-Regione Toscana, Italy.

出版信息

Cardiovasc Revasc Med. 2018 Apr-May;19(3 Pt B):390-392. doi: 10.1016/j.carrev.2017.08.001. Epub 2017 Aug 12.

DOI:10.1016/j.carrev.2017.08.001
PMID:28923693
Abstract

Drug-coated balloons (DCB) are being used for in-stent restenosis treatment and there is some preliminary experience in other coronary settings, including small vessels and side branches. Scoring balloons (SB) are a useful tool for the preparation of fibro-calcific lesions. Because of the controlled micro-dissections that SB induce, it has been hypothesized that they may have a role in helping paclitaxel deliverability inside the vessel wall. The AngioSculpt®X (Spectranetics) is a novel paclitaxel-coated SB with encouraging preliminary data for the treatment of in-stent restenosis. We here describe our first experience treating two de novo coronary lesions with angiographic follow up.

摘要

药物涂层球囊(DCB)正被用于支架内再狭窄的治疗,并且在其他冠状动脉病变情况中也有一些初步经验,包括小血管和分支血管。刻痕球囊(SB)是用于准备纤维钙化病变的一种有用工具。由于SB所引发的可控性微切割,有人推测它们可能在帮助紫杉醇向血管壁内递送方面发挥作用。AngioSculpt®X(Spectranetics公司)是一种新型的紫杉醇涂层刻痕球囊,其在治疗支架内再狭窄方面有令人鼓舞的初步数据。我们在此描述我们首次使用其治疗两处初发冠状动脉病变并进行血管造影随访的经验。

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