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尼日利亚患者的移植旅游益处是否大于风险?单中心经验。

Do the Benefits of Transplant Tourism Amongst Nigerian Patients Outweigh the Risks? A Single-Center Experience.

作者信息

Amira C O, Bello B T

机构信息

Nephrology Unit, Department of Medicine, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria.

出版信息

Int J Organ Transplant Med. 2017;8(3):132-139. Epub 2017 Aug 1.

PMID:28924461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5592100/
Abstract

BACKGROUND

Transplant tourism (TT) is the term used to describe travel outside one's country of abode for the sole purpose of obtaining organ transplantation services.

OBJECTIVE

This study describes the characteristics and outcomes of kidney transplant tourists who were followed up in our institution.

METHODS

A retrospective study was conducted on patients who underwent kidney transplantation outside the country and were followed up in our institution from 2007 to 2015.

RESULTS

26 patients were followed up; 19 (73%) were males. The mean±SD age of patients was 40.5±10.3 years. The majority (n=20) of the transplantations were carried out in India. Living-unrelated transplants were most common (54%). Complications encountered were infections in 11 (42%) patients, new-onset diabetes after transplantation in 9 (35%), chronic allograft nephropathy in 8 (31%), biopsy-proven acute rejections in 3 (12%), and primary non-function in 2 (8%). 1-year graft survival was 81% and 1-year patient survival was 85%.

CONCLUSION

Kidney transplant tourism is still common among Nigerian patients with end-stage renal disease. Short-term graft and patient survival rates were poorer than values recommended for living kidney transplants. We therefore advise that TT should be discouraged in Nigeria, given the availability of transplantation services in the country, and also in line with international efforts to curb the practice.

摘要

背景

移植旅游(TT)是用于描述为获取器官移植服务而前往居住国境外旅行的术语。

目的

本研究描述了在我们机构接受随访的肾移植游客的特征和结局。

方法

对2007年至2015年在国外接受肾移植并在我们机构接受随访的患者进行了一项回顾性研究。

结果

对26例患者进行了随访;19例(73%)为男性。患者的平均年龄±标准差为40.5±10.3岁。大多数移植(n = 20)在印度进行。活体非亲属移植最为常见(54%)。遇到的并发症包括11例(42%)患者发生感染,9例(35%)患者移植后新发糖尿病,8例(31%)患者发生慢性移植肾肾病,3例(12%)患者经活检证实发生急性排斥反应,2例(8%)患者发生原发性无功能。1年移植肾存活率为81%,1年患者存活率为85%。

结论

肾移植旅游在尼日利亚终末期肾病患者中仍然很常见。短期移植肾和患者存活率低于活体肾移植推荐值。因此,鉴于尼日利亚有移植服务,并且也符合国际上遏制这种做法的努力,我们建议在尼日利亚应劝阻移植旅游。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a331/5592100/8874467cc3e9/ijotm-8-132-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a331/5592100/8874467cc3e9/ijotm-8-132-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a331/5592100/8874467cc3e9/ijotm-8-132-g001.jpg

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本文引用的文献

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Kidney Int Suppl (2011). 2013 May;3(2):241-245. doi: 10.1038/kisup.2013.23.
2
What are the key challenges we face in kidney transplantation today?如今我们在肾脏移植中面临的关键挑战有哪些?
Transplant Res. 2013 Nov 20;2(Suppl 1):S1. doi: 10.1186/2047-1440-2-S1-S1.
3
Key issues in transplant tourism.移植旅游中的关键问题。
The current status of kidney transplantation in Nigerian children: still awaiting light at the end of the tunnel.
目前尼日利亚儿童肾移植的状况:仍在等待隧道尽头的曙光。
Pediatr Nephrol. 2021 Mar;36(3):693-699. doi: 10.1007/s00467-020-04753-7. Epub 2020 Sep 24.
4
Developing nephrology services in low income countries: a case of Tanzania.在低收入国家发展肾脏病服务:以坦桑尼亚为例。
BMC Nephrol. 2019 Oct 17;20(1):378. doi: 10.1186/s12882-019-1568-7.
World J Transplant. 2012 Feb 24;2(1):9-18. doi: 10.5500/wjt.v2.i1.9.
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Ethical and legal implications of the risks of medical tourism for patients: a qualitative study of Canadian health and safety representatives' perspectives.医疗旅游对患者风险的伦理和法律影响:加拿大卫生和安全代表观点的定性研究。
BMJ Open. 2013 Feb 8;3(2). doi: 10.1136/bmjopen-2012-002302. Print 2013.
5
Commercial kidney transplantation: trends, outcomes and challenges-a single-centre experience.商业性肾移植:趋势、结果与挑战——单中心经验
Ann Afr Med. 2012 Apr-Jun;11(2):70-4. doi: 10.4103/1596-3519.93527.
6
Commercial renal transplantation: A risky venture? A single Canadian centre experience.商业性肾移植:一项冒险之举?加拿大一个中心的经验。
Can Urol Assoc J. 2011 Oct;5(5):335-40. doi: 10.5489/cuaj.11018.
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