Department of Internal Medicine, University of Abuja, Gwagwalada, Abuja, Nigeria.
Department of Internal Medicine, University of Medical Sciences, Ondo, Ondo State, Nigeria.
J Nephrol. 2024 Jul;37(6):1669-1677. doi: 10.1007/s40620-024-02019-1. Epub 2024 Jul 16.
Kidney transplantation is the best mode of kidney replacement therapy. However, the shortage of organ donations has been a major challenge globally. Relatives of patients with end-stage kidney disease (ESKD) are potential kidney donors. We explored their perspectives about kidney donation, kidney commercialisation, and barriers to kidney donation.
In-depth interviews were conducted among 28 relatives of ESKD patients across the six geopolitical zones and Federal Capital Territory of Nigeria. The interview focused on potential sources of kidney donors, kidney commercialisation and barriers to kidney donation. ATLAS.ti version 9.0.22.0 was used for data analysis.
Mean age of the study participants was 41.57 ± 14.55 years; 54% were females, 60.7% were married, 93% had tertiary education and 75% were first degree relatives of ESKD patients. There were 7 themes and 28 subthemes generated in this study. The potential sources of kidney donors identified by the study participants included commercial, hospital, family and non-family member donors. While some opined that a family member is the best choice as a kidney donor, others preferred a commercial donor. The majority of those interviewed do not believe that it is wrong to purchase a kidney, and would be willing to do so. Identified factors that promote kidney commercialisation were unwillingness of a family member to donate, having the financial capacity to purchase a kidney, non-fitness of family members to donate. Identified barriers to kidney donation were age, poor health status, polygamy, perceived poor expertise of the medical team, perceived risk of the procedure, parental influence and religious beliefs.
The majority of participants lacked correct information about kidney donation. Implementation of educational program policies and laws regulating and reinforcing ethical principles of kidney donation and transplantation should be ensured.
肾移植是肾脏替代治疗的最佳方式。然而，器官捐献的短缺一直是全球的一个主要挑战。终末期肾病（ESKD）患者的亲属是潜在的肾脏捐献者。我们探讨了他们对肾脏捐献、肾脏商业化以及肾脏捐献障碍的看法。
在尼日利亚的六个地缘政治区和联邦首都区，对 28 名 ESKD 患者亲属进行了深入访谈。访谈重点是潜在的肾脏捐献者来源、肾脏商业化和肾脏捐献障碍。使用 ATLAS.ti 版本 9.0.22.0 进行数据分析。
研究参与者的平均年龄为 41.57±14.55 岁；54%为女性，60.7%已婚，93%接受过高等教育，75%为 ESKD 患者的一级亲属。本研究共产生了 7 个主题和 28 个子主题。研究参与者确定的潜在肾脏捐献者来源包括商业、医院、家庭和非家庭成员捐献者。虽然一些人认为家庭成员是最好的肾脏捐献者选择，但其他人则更喜欢商业捐献者。大多数接受采访的人并不认为购买肾脏是错误的，并且愿意这样做。促进肾脏商业化的因素包括家庭成员不愿意捐献、有购买肾脏的经济能力、家庭成员不适合捐献。肾脏捐献的障碍包括年龄、健康状况不佳、一夫多妻制、认为医疗团队专业知识不足、认为手术风险大、父母的影响和宗教信仰。
大多数参与者对肾脏捐献缺乏正确的认识。应确保实施教育计划、政策和法律，规范和加强肾脏捐献和移植的伦理原则。
