Suppr超能文献

全省症状筛查是否改变了老年癌症患者的阿片类药物处方率?

Has Province-Wide Symptom Screening Changed Opioid Prescribing Rates in Older Patients With Cancer?

作者信息

Barbera Lisa, Sutradhar Rinku, Chu Anna, Seow Hsien, Earle Craig C, O'Brien Mary Ann, Dudgeon Deborah, DeAngelis Carlo, Atzema Clare, Husain Amna, Liu Ying, Howell Doris

机构信息

Odette Cancer Centre, Sunnybrook Health Sciences Centre; Institute for Clinical Evaluative Sciences; University of Toronto; Sunnybrook Health Sciences Centre; Mount Sinai Hospital, Temmy Latner Centre for Palliative Care; University Health Network, Princess Margaret Hospital, Toronto; McMaster University, Hamilton; and Queen's University, Kingston, Ontario, Canada.

出版信息

J Oncol Pract. 2017 Nov;13(11):e927-e934. doi: 10.1200/JOP.2017.025494. Epub 2017 Sep 19.

Abstract

PURPOSE

Previous work in Ontario demonstrated that 33% of patients with cancer with severe pain did not receive opioids at the time of their pain assessment. With efforts to increase symptom screening and management since then, the objective of this study was to examine temporal trends in opioid prescribing.

METHODS

The cohort was comprised of Ontario residents ≥ 65 years of age with a cancer history who were eligible for the government pharmacare program and had a pain assessment using the Edmonton Symptom Assessment System. Use of the Edmonton Symptom Assessment System is part of a provincial initiative to screen ambulatory patients with cancer for symptoms. Annually between 2007 and 2013, we used the date of an individual's highest pain score as the index date to calculate annual opioid prescription rates for claims within 30 days before and up to 7 days after the index date. A logistic regression model evaluated the association between index year and odds of receiving an opioid prescription.

RESULTS

During the study period, the number of individuals undergoing symptom assessment annually increased more than eight-fold. Opioid prescription rates were directly related to pain scores, but there was an annual 5% relative decrease in the odds of receiving an opioid prescription during the era from 2009 to 2013.

CONCLUSION

We are doing better at screening for pain, but this has not led to an increase in analgesic intervention for those identified. Additional work is required to determine what opioid prescribing rate is optimal to ensure we are not missing opportunities to improve patient comfort.

摘要

目的

安大略省之前的研究表明,33%的重度疼痛癌症患者在疼痛评估时未接受阿片类药物治疗。自那时起,随着加强症状筛查和管理工作的开展,本研究的目的是探讨阿片类药物处方的时间趋势。

方法

该队列由年龄≥65岁、有癌症病史、符合政府药物保险计划资格且使用埃德蒙顿症状评估系统进行疼痛评估的安大略省居民组成。使用埃德蒙顿症状评估系统是该省一项针对癌症门诊患者进行症状筛查倡议的一部分。在2007年至2013年期间,我们每年将个人最高疼痛评分日期作为索引日期,计算索引日期前30天内及索引日期后7天内索赔的年度阿片类药物处方率。采用逻辑回归模型评估索引年份与接受阿片类药物处方几率之间的关联。

结果

在研究期间,每年接受症状评估的人数增加了八倍多。阿片类药物处方率与疼痛评分直接相关,但在2009年至2013年期间,接受阿片类药物处方的几率每年相对下降5%。

结论

我们在疼痛筛查方面做得更好,但这并未导致对已确诊患者的镇痛干预增加。需要开展更多工作来确定最佳的阿片类药物处方率,以确保我们不会错过改善患者舒适度的机会。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验