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130例脑室联合神经内镜手术结果,重点关注穹窿挫伤

Results of Combined Intraventricular Neuroendoscopic Procedures in 130 Cases with Special Focus on Fornix Contusions.

作者信息

Oertel Joachim, Linsler Stefan, Emmerich Caroline, Keiner Dörthe, Gaab Michael, Schroeder Henry, Senger Sebastian

机构信息

Department of Neurosurgery, Medical School of the Saarland University, Homburg/Saar, Germany.

Department of Neurosurgery, Medical School of the Saarland University, Homburg/Saar, Germany.

出版信息

World Neurosurg. 2017 Dec;108:817-825. doi: 10.1016/j.wneu.2017.09.045. Epub 2017 Sep 18.

Abstract

OBJECTIVE

Increasing experience with intraventricular neuroendoscopic procedures shows good results in the combination of endoscopic third ventriculostomy (ETV) and tumor biopsy. Other possible combinations are mainly presented in subgroups in the literature. Here, we present our experience with combined intraventricular procedures within 1 setting over the last 2 decades.

METHODS

This study retrospectively analyzes data from neuroendoscopic intraventricular procedures between 1993 and 2015 in 3 different departments of neurosurgery. Inclusion criteria were a combination of at least 2 intraventricular endoscopic procedures (e.g. third ventriculostomy, cyst fenestration, tumor surgery or aqueductoplasty) within 1 setting.

RESULTS

One-hundred and thirty cases with more than 300 procedures fulfilled the inclusion criteria. The most frequent combinations were ETV and tumor biopsy (n = 36), ETV and aqueductoplasty/stenting (n = 30), and ETV and cyst fenestration (n = 18). The complication rate was 16.9% with an overall morbidity of 1.6% and mortality of 0.8%. Fornix contusion was one of the most frequent intraoperative complications (16.4%). Shunt independency was achieved in 82.9% of cases with hydrocephalic symptoms.

CONCLUSIONS

A combination of different intraventricular endoscopic procedures is safe and reliable, bearing similar risks of morbidities and mortality to single neuroendoscopic procedures. This study is one of the largest series in the literature and has similar low complication rates to others. Fornix contusion is the most frequent intraoperative complication in these patients. However, obvious clinical correlation is rare.

摘要

目的

随着脑室内神经内镜手术经验的增加,内镜下第三脑室造瘘术(ETV)与肿瘤活检联合应用显示出良好效果。其他可能的联合方式在文献中主要以亚组形式呈现。在此,我们介绍过去20年内在同一手术环境下进行联合脑室内手术的经验。

方法

本研究回顾性分析了1993年至2015年期间3个不同神经外科科室脑室内神经内镜手术的数据。纳入标准为在同一手术环境下至少进行2种脑室内内镜手术(如第三脑室造瘘术、囊肿开窗术、肿瘤手术或导水管成形术)的联合。

结果

130例患者接受了超过300次手术,符合纳入标准。最常见的联合方式为ETV与肿瘤活检(n = 36)、ETV与导水管成形术/支架置入术(n = 30)以及ETV与囊肿开窗术(n = 18)。并发症发生率为16.9%,总体发病率为1.6%,死亡率为0.8%。穹窿挫伤是最常见的术中并发症之一(16.4%)。82.9%有脑积水症状的患者实现了分流独立。

结论

不同脑室内内镜手术的联合是安全可靠的,其发病率和死亡率风险与单一神经内镜手术相似。本研究是文献中最大的系列研究之一,并发症发生率与其他研究相似且较低。穹窿挫伤是这些患者最常见的术中并发症。然而,明显的临床相关性很少见。

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