Tellechea Juan Ignacio, Gonzalez Jean-Michel, Miranda-García Pablo, Culetto Adrian, D'Journo Xavier Benoit, Thomas Pascal Alexandre, Barthet Marc
Department of Gastroenterology, North Hospital, University of Mediterranean, Chemin des Bourrely, Marseille, France.
Department of Thoracic Surgical, North Hospital, University of Mediterranean, Chemin des Bourrely, Marseille, France.
Clin Endosc. 2018 Mar;51(2):186-191. doi: 10.5946/ce.2017.043. Epub 2017 Sep 20.
Boerhaave syndrome (BS) is a spontaneous esophageal perforation which carries high mortality. Surgical treatment is well established, but the development of interventional endoscopy has proposed new therapies. We expose our experience in a Gastrointestinal and Endoscopy Unit. With a retrospective, observational, open-label, single center, consecutive case series. All patients diagnosed with BS who were managed in our center were included. Treated conservatively, endoscopically or surgically, according to their clinical condition and lesion presentation. Fourteen patients were included. Ten were treated with primary surgery. One conservatively. In total, 7/14 patients required an endoscopic treatment. All required metallic stents deployment, 3 cases over-the-scope-clips concomitantly and one case a novel technique an internal drain. 6/7 cases endoscopically treated achieved complete esophageal healing. In conclusion, endoscopy is an useful tool at all stages BS management: difficult diagnosis, primary treatment in selected patients and as salvage when surgery fails. With mortality rates and outcomes comparables to surgery.
博雷尔哈夫综合征(BS)是一种自发性食管穿孔,死亡率很高。手术治疗已很成熟,但介入内镜的发展提出了新的治疗方法。我们展示了在胃肠和内镜科的经验。采用回顾性、观察性、开放标签、单中心、连续病例系列研究。纳入了所有在我们中心确诊为BS并接受治疗的患者。根据他们的临床状况和病变表现,分别采用保守治疗、内镜治疗或手术治疗。共纳入14例患者。10例接受了一期手术,1例接受了保守治疗。总共7/14的患者需要内镜治疗。所有患者均需置入金属支架,3例同时使用了套扎夹,1例采用了一种新技术——内置引流管。7例接受内镜治疗的患者中有6例食管完全愈合。总之,内镜在BS管理的各个阶段都是一种有用的工具:诊断困难时、对选定患者进行初步治疗以及手术失败时作为挽救措施。其死亡率和治疗效果与手术相当。