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罗哌卡因用于中线结直肠手术患者双侧腹横肌平面阻滞的术后镇痛效果:一项随机、双盲、安慰剂对照试验

Postoperative Analgesic Efficacy of Bilateral Transversus Abdominis Plane Block in Patients Undergoing Midline Colorectal Surgeries Using Ropivacaine: A Randomized, Double-blind, Placebo-controlled Trial.

作者信息

Qazi Nahida, Bhat Wasim Mohammad, Iqbal Malik Zaffar, Wani Anisur Rehman, Gurcoo Showkat A, Rasool Sahir

机构信息

Department of Anaesthesia and Critical Care, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

出版信息

Anesth Essays Res. 2017 Jul-Sep;11(3):767-772. doi: 10.4103/0259-1162.194577.

Abstract

BACKGROUND

Ultrasound-guided transversus abdominis plane (TAP) block is done as a part of multimodal analgesia for pain relief after abdominal surgeries. This prospective randomized, double-blind, placebo-controlled trial was conducted to evaluate the postoperative analgesic efficacy of bilateral TAP block in patients undergoing midline colorectal surgeries using ropivacaine.

MATERIALS AND METHODS

Eighty patients scheduled for elective colorectal surgeries involving midline abdominal wall incision under general anesthesia were enrolled in this prospective randomized controlled trial. Group A received TAP block with 20 ml of 0.2% ropivacaine on either side of the abdominal wall, and Group B received 20 ml of normal saline. The time to request for rescue analgesia, total analgesic consumption in 24 h, and satisfaction with the anesthetic technique were assessed.

RESULTS

The mean visual analog scale scores at rest and on coughing were higher in control group ( > 0.05). Time (min) to request for the first rescue analgesia was prolonged in study group compared to control group ( < 0.001). The total tramadol consumption in 24 h postoperatively was significantly high in control group ( < 0.001). Nausea/vomiting was more common in control group ( > 0.05). The level of satisfaction concerning postoperative pain control/anesthetic technique was higher in study group ( < 0.001).

CONCLUSION

TAP block produces effective and prolonged postoperative analgesia in patients undergoing midline colorectal surgery. It is a technically simple block to perform with a high margin of safety. It produces a considerable reduction in mean intravenous postoperative tramadol requirements, reduction in postoperative pain scores, and increased time to first request for further analgesia, both at rest and on movement.

摘要

背景

超声引导下腹横肌平面(TAP)阻滞作为腹部手术后多模式镇痛的一部分用于缓解疼痛。本前瞻性随机、双盲、安慰剂对照试验旨在评估使用罗哌卡因对接受中线结直肠手术患者进行双侧TAP阻滞的术后镇痛效果。

材料与方法

本前瞻性随机对照试验纳入了80例计划在全身麻醉下进行涉及中线腹壁切口的择期结直肠手术的患者。A组在腹壁两侧接受20 ml 0.2%罗哌卡因的TAP阻滞,B组接受20 ml生理盐水。评估患者要求使用补救镇痛的时间、24小时内的总镇痛药物消耗量以及对麻醉技术的满意度。

结果

对照组静息和咳嗽时的平均视觉模拟量表评分更高(P>0.05)。与对照组相比,研究组首次要求使用补救镇痛的时间(分钟)延长(P<0.001)。对照组术后24小时曲马多的总消耗量显著更高(P<0.001)。恶心/呕吐在对照组中更常见(P>0.05)。研究组对术后疼痛控制/麻醉技术的满意度更高(P<0.001)。

结论

TAP阻滞在接受中线结直肠手术的患者中产生有效且持久的术后镇痛效果。它是一种技术操作简单且安全性高的阻滞方法。它能显著降低术后静脉注射曲马多的平均需求量,降低术后疼痛评分,并延长静息和活动时首次要求进一步镇痛的时间。

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