Beal Christopher A, Krouse Michael C, Tubbs Jeffrey T
a Spinal Cord Injury Service and Disorders , Hunter Holmes McGuire VA Medical Center , Richmond , Virginia , USA.
b Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University , Richmond , Virginia , USA.
J Spinal Cord Med. 2018 Sep;41(5):571-574. doi: 10.1080/10790268.2017.1375722. Epub 2017 Sep 20.
a single case report.
To report a case of a patient with tetraplegia who developed acute promyelocytic leukemia (APL) while in inpatient rehabilitation after 10.5 months.
A VA Medical Center Spinal Cord Injury Service and Disorders Unit Case Report: A 47 year-old male with a stage IV sacral pressure ulcer and C4 AIS A complete tetraplegia secondary to a motor vehicle collision, developed fever, thrombocytopenia, and anemia 20 months after his injury while in inpatient rehabilitation and was found to have APL, confirmed following bone marrow biopsy.
There is a wide differential for fever after a spinal cord injury. In this case report, the source of fever was APL. It is important as healthcare providers to not overlook fevers when otherwise common causes do not fit the clinical picture. Additionally, there has been no association found between traumatic spinal cord injury and the development of acute leukemia, however this is the first case report. Therefore, it is important to continue investigating to determine if an association exists.
单病例报告。
报告1例四肢瘫痪患者，在住院康复10.5个月后发生急性早幼粒细胞白血病（APL）的病例。
一家退伍军人医疗中心脊髓损伤服务与疾病科病例报告：一名47岁男性，因机动车碰撞导致IV期骶部压疮和C4级美国脊髓损伤协会（AIS）A级完全性四肢瘫痪，受伤20个月后在住院康复期间出现发热、血小板减少和贫血，经骨髓活检确诊为APL。
脊髓损伤后发热的鉴别诊断范围广泛。在本病例报告中，发热源为APL。作为医疗服务提供者，当常见病因不符合临床表现时，切勿忽视发热情况，这一点很重要。此外，尚未发现创伤性脊髓损伤与急性白血病的发生之间存在关联，但这是首例病例报告。因此，继续进行调查以确定是否存在关联很重要。
