1Faculty of Pharmacy and Pharmaceutical Sciences,University of Alberta,Edmonton,Alberta,Canada.
Can J Neurol Sci. 2018 Jan;45(1):49-55. doi: 10.1017/cjn.2017.233. Epub 2017 Sep 20.
Pharmacists have become an integral member of the multidisciplinary team providing clinical patient care in various healthcare settings. Although evidence supporting their role in the care of patients with other disease states is well-established, minimal literature has been published evaluating pharmacist interventions in stroke patients. The purpose of this systematic review is to summarize the evidence evaluating the impact of pharmacist interventions on stroke patient outcomes.
Study abstracts and full-text articles evaluating the impact of a pharmacist intervention on outcomes in patients with an acute stroke/transient ischemic attack (TIA) or a history of an acute stroke/TIA were identified and a qualitative analysis performed.
A total of 20 abstracts and full-text studies were included. The included studies provided evidence supporting pharmacist interventions in multiple settings, including emergency departments, inpatient, outpatient, and community pharmacy settings. In a significant proportion of the studies, pharmacist care was collaborative with other healthcare professionals. Some of the pharmacist interventions included participation in a stroke response team, assessment for thrombolytic use, medication reconciliation, participation in patient rounds, identification and resolution of drug therapy problems, risk-factor reduction, and patient education. Pharmacist involvement was associated with increased use of evidence-based therapies, medication adherence, risk-factor target achievement, and maintenance of health-related quality of life.
Available evidence suggests that a variety of pharmacist interventions can have a positive impact on stroke patient outcomes. Pharmacists should be considered an integral member of the stroke patient care team.
药剂师已成为多学科团队的重要成员,在各种医疗保健环境中为患者提供临床护理。尽管有大量证据支持药剂师在治疗其他疾病患者中的作用,但发表的关于评估药剂师干预对卒中患者影响的文献却很少。本系统评价的目的是总结评估药师干预对卒中患者结局影响的证据。
确定并进行了定性分析了评估药师干预对急性卒中和短暂性脑缺血发作(TIA)患者或有急性卒中和 TIA 病史患者结局影响的研究摘要和全文。
共纳入 20 篇摘要和全文研究。这些纳入的研究提供了在多个环境中(包括急诊科、住院部、门诊部和社区药房)开展药师干预的证据。在相当一部分研究中,药师护理与其他医疗保健专业人员合作开展。一些药师干预措施包括参与卒中反应小组、评估溶栓治疗的使用、药物重整、参与患者查房、识别和解决药物治疗问题、降低风险因素以及患者教育。药师的参与与更广泛使用基于证据的治疗方法、药物依从性、风险因素目标的实现以及维持健康相关的生活质量有关。
现有证据表明,各种药师干预措施可能对卒中患者的结局产生积极影响。药师应被视为卒中患者护理团队的重要成员。