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Surgery: KRAS mutations and hepatic recurrence after treatment of colorectal liver metastases.

作者信息

Brudvik Kristoffer Watten, Vauthey Jean-Nicolas

机构信息

Department of Hepato-Pancreato-Biliary Surgery, Oslo University Hospital, PO Box 4950 Nydalen, 0424 Oslo, Norway.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1484, Houston, Texas 77030, USA.

出版信息

Nat Rev Gastroenterol Hepatol. 2017 Nov;14(11):638-639. doi: 10.1038/nrgastro.2017.129. Epub 2017 Sep 20.

DOI:10.1038/nrgastro.2017.129
PMID:28930294
Abstract
摘要

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5
Effect of KRAS Mutation on Long-Term Outcomes of Patients Undergoing Hepatic Resection for Colorectal Liver Metastases.KRAS 突变对接受肝切除治疗结直肠癌肝转移患者长期预后的影响。
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本文引用的文献

1
Anatomical Resections Improve Disease-free Survival in Patients With KRAS-mutated Colorectal Liver Metastases.KRAS 突变型结直肠癌肝转移患者行解剖性肝切除可改善无病生存。
Ann Surg. 2017 Oct;266(4):641-649. doi: 10.1097/SLA.0000000000002367.
2
Local tumour progression after percutaneous ablation of colorectal liver metastases according to RAS mutation status.根据RAS突变状态，经皮消融结直肠癌肝转移灶后的局部肿瘤进展情况。
Br J Surg. 2017 May;104(6):760-768. doi: 10.1002/bjs.10490. Epub 2017 Feb 27.
3
RAS Mutation Predicts Positive Resection Margins and Narrower Resection Margins in Patients Undergoing Resection of Colorectal Liver Metastases.
基因数据在结直肠癌肝转移外科治疗中的影响及临床应用价值：一篇叙述性综述
Hepatobiliary Surg Nutr. 2020 Dec;9(6):705-716. doi: 10.21037/hbsn.2019.10.05.
4
Colorectal liver metastases: Current management and future perspectives.结直肠癌肝转移：当前治疗与未来展望
World J Clin Oncol. 2020 Oct 24;11(10):761-808. doi: 10.5306/wjco.v11.i10.761.
5
Laparoscopic liver resection for non-colorectal non-neuroendocrine metastases: perioperative and oncologic outcomes.腹腔镜肝切除术治疗非结直肠非神经内分泌转移瘤：围手术期和肿瘤学结果。
World J Surg Oncol. 2019 Sep 4;17(1):156. doi: 10.1186/s12957-019-1700-y.
6
The Prognostic Impact of KRAS Mutation in Patients Having Curative Resection of Synchronous Colorectal Liver Metastases.KRAS 基因突变对同步结直肠肝转移瘤根治性切除术后患者预后的影响。
J Gastrointest Surg. 2019 Oct;23(10):1957-1963. doi: 10.1007/s11605-018-3978-4. Epub 2018 Oct 1.
7
Colorectal Liver Metastases: Does the Future of Precision Medicine Lie in Genetic Testing?结直肠癌肝转移：精准医学的未来是否在于基因检测？
J Gastrointest Surg. 2018 Jul;22(7):1286-1296. doi: 10.1007/s11605-018-3766-1. Epub 2018 Apr 11.
RAS突变可预测接受结直肠癌肝转移灶切除患者的切缘阳性及切缘较窄情况。
Ann Surg Oncol. 2016 Aug;23(8):2635-43. doi: 10.1245/s10434-016-5187-2. Epub 2016 Mar 25.
4
Complete removal of the tumor-bearing portal territory decreases local tumor recurrence and improves disease-specific survival of patients with hepatocellular carcinoma.完整切除肿瘤累及的门静脉区域可降低肝癌患者局部肿瘤复发率并提高疾病特异性生存率。
J Hepatol. 2016 Mar;64(3):594-600. doi: 10.1016/j.jhep.2015.10.015. Epub 2015 Oct 24.
5
Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases.结直肠癌肝转移切除术后 KRAS 突变与生存的荟萃分析。
Br J Surg. 2015 Sep;102(10):1175-83. doi: 10.1002/bjs.9870. Epub 2015 Jul 21.
6
RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases.RAS 基因突变状态可预测行肝切除术的结直肠癌肝转移患者的生存和复发模式。
Ann Surg. 2013 Oct;258(4):619-26; discussion 626-7. doi: 10.1097/SLA.0b013e3182a5025a.
7
Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases.结直肠癌肝转移灶肝楔形切除术与解剖性切除术的比较。
J Gastrointest Surg. 2006 Jan;10(1):86-94. doi: 10.1016/j.gassur.2005.07.022.
8
Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases.手术切缘状态对结直肠癌肝转移灶切除术后生存及复发部位的影响。
Ann Surg. 2005 May;241(5):715-22, discussion 722-4. doi: 10.1097/01.sla.0000160703.75808.7d.
9
Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells.致癌性K-RAS是维持结肠癌细胞细胞骨架组织、黏附及运动性变化所必需的。
Cancer Res. 2005 Feb 15;65(4):1244-50. doi: 10.1158/0008-5472.CAN-04-1911.
10
Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined resection/ablation for colorectal liver metastases.结直肠癌肝转移患者肝切除、射频消融及联合切除/消融后的复发情况及预后
Ann Surg. 2004 Jun;239(6):818-25; discussion 825-7. doi: 10.1097/01.sla.0000128305.90650.71.