Manjusha P, Sudha S, Shameena P M, Chandni R, Varma Sujatha, Pandiar Deepak
Department of Oral Pathology and Microbiology, Government Dental College, Kozhikode, Kerala, India.
Department of Oral Pathology and Microbiology, Government Dental College, Alappuzha, Kerala, India.
J Oral Maxillofac Pathol. 2017 May-Aug;21(2):309-315. doi: 10.4103/jomfp.JOMFP_17_16.
Globally, the prevalence of diabetes is soaring high in the recent times. There is an ardent search in the scientific community for a reliable and cheap early predictor which can serve the purpose of mass screening of a genetically vulnerable population. Hence, the present study was conducted to assess the predictive role of cheiloscopy on type II diabetes mellitus (T2DM). Several studies have established the association of dermatoglyphics with diabetes. However, results are still far from satisfaction. Thus, we also evaluated fingerprint analysis along with cheiloscopy.
The study was conducted on 100 uncontrolled T2DM patients and 50 healthy controls. Lip prints were obtained using lipstick and cellophane paper analyzed and classified using Suzuki and Tsuchihashi's classification. Fingerprints were obtained using kajal stick, analyzed and classified using Henry's system of classification.
Type IV pattern of lip prints was found significantly more in the diabetic patients. Howbeit, fingerprint analysis did not reveal any significant association with diabetes.
The present study showed a ray of hope for application of cheiloscopy as a potential biomarker in the early diagnosis of T2DM which can be used in mass screening. Further studies are warranted to confirm the findings.
在全球范围内，糖尿病的患病率近年来急剧飙升。科学界正在热切寻找一种可靠且廉价的早期预测指标，以用于对遗传易感性人群进行大规模筛查。因此，开展本研究以评估唇纹检查对2型糖尿病（T2DM）的预测作用。多项研究已证实皮纹与糖尿病之间的关联。然而，结果仍不尽人意。因此，我们还将指纹分析与唇纹检查一同进行了评估。
本研究对100例未控制的T2DM患者和50例健康对照者进行。使用口红和玻璃纸获取唇纹，采用铃木和土桥分类法进行分析和分类。使用眼线笔获取指纹，采用亨利分类系统进行分析和分类。
在糖尿病患者中，IV型唇纹模式的出现频率显著更高。然而，指纹分析未显示出与糖尿病有任何显著关联。
本研究为唇纹检查作为T2DM早期诊断的潜在生物标志物的应用带来了一线希望，可用于大规模筛查。需要进一步研究来证实这些发现。
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