Department of Anatomy, Faculty of Medicine, University of Niš, 81 Blvd. Dr. Zoran Djindjić, 18000 Niš, Serbia.
Health Center Niš, 15 Vojvode Tankosića St., 18000 Niš, Serbia.
Biomed Res Int. 2017;2017:7238672. doi: 10.1155/2017/7238672. Epub 2017 Aug 28.
Morphological characteristics of 108 cases of uni- and bilateral aplasia of the vertebral artery (VA) in reports or images of retrospective studies, including one recent case, published between 1967 and 2016 are analyzed. Incidence, gender, persistence of carotid-vertebrobasilar anastomosis (CVBA), associated with other vascular variants, and vascular pathology in each group of uni- and bilateral VA aplasia are mutually compared. Most of the cases of VA aplasia in ages 31 to 80 were discovered in USA, Japan, and India. The bilateral VA aplasia is more common in the male gender than in the female one. The side of the VA aplasia had a significant effect on the side of CVBA persistence. Associated aplasia of other arteries was more common in cases of unilateral VA aplasia. The left VA was more commonly hypoplastic in cases of single right VA aplasia than the right VA in cases of single left VA aplasia. Aneurysms of definitive arteries were more frequent in cases of single right VA aplasia than in cases of single left VA aplasia. We claim that the aplasia of the VA probably depends on genetic factors in some races, while diseases are expressed usually in persons over 30 years of age.
对 1967 年至 2016 年间发表的 108 例单侧和双侧椎动脉（VA）发育不全的报告或回顾性研究图像中的形态特征进行分析，包括 1 例近期病例。对单侧和双侧 VA 发育不全的各组发生率、性别、颈-椎基底动脉吻合（CVBA）的持久性、与其他血管变异的关系以及血管病理学进行相互比较。31 岁至 80 岁的 VA 发育不全病例多在美国、日本和印度发现。双侧 VA 发育不全在男性中比女性更常见。VA 发育不全的一侧对 CVBA 持久性的一侧有显著影响。单侧 VA 发育不全时，其他动脉的同时发育不全更为常见。在单侧右 VA 发育不全的情况下，左 VA 比单侧左 VA 发育不全的情况下更常发育不全。在单侧右 VA 发育不全的情况下，明确动脉的动脉瘤比单侧左 VA 发育不全的情况下更常见。我们认为，VA 的发育不全可能在某些种族中取决于遗传因素，而疾病通常在 30 岁以上的人群中表现出来。
