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创伤性脑损伤后的睡眠障碍

Sleep Disturbance After TBI.

作者信息

Barshikar Surendra, Bell Kathleen R

机构信息

Department of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center, 5151 Harry Hines Blvd, 1st Floor, Suite 104, Dallas, TX, 75390-9055, USA.

出版信息

Curr Neurol Neurosci Rep. 2017 Sep 20;17(11):87. doi: 10.1007/s11910-017-0792-4.

Abstract

PURPOSE OF REVIEW

Present relevant literature to update knowledge on sleep science, identify common sleep disturbances seen in TBI, discuss evidence for available treatment options, and illuminate future areas for research.

RECENT FINDINGS

Sleep disturbances, including insomnia, circadian rhythm disturbances, and sleep apnea, are prevalent for all severities of traumatic brain injury (TBI), can be chronic, and affect both rehabilitation and recovery from the TBI. New knowledge of basic sleep mechanisms and neurochemistry has exploded in the last decade. In addition to known effects on mood and cognition from sleep deprivation in persons with TBI, new evidence indicates potential deleterious effects on neurorecovery and acceleration of long-term neurodegeneration.

摘要

综述目的

呈现相关文献以更新睡眠科学知识,识别创伤性脑损伤(TBI)中常见的睡眠障碍,讨论现有治疗选择的证据,并阐明未来的研究领域。

最新发现

睡眠障碍,包括失眠、昼夜节律紊乱和睡眠呼吸暂停,在所有严重程度的创伤性脑损伤(TBI)中都很普遍,可能是慢性的,并且会影响TBI的康复和恢复。在过去十年中,基础睡眠机制和神经化学方面的新知识激增。除了已知TBI患者睡眠剥夺对情绪和认知的影响外,新证据表明对神经恢复和长期神经退行性变加速有潜在有害影响。

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