Pinto Carneiro J B, Pinto de Souza T, Antunes de Oliveira T M L, Euzébio Ribeiro S L
Rheumatology Section, University Hospital Getúlio Vargas/Federal University of Amazonas.
Reumatismo. 2017 Sep 21;69(3):126-130. doi: 10.4081/reumatismo.2017.993.
We report two cases of siblings presenting coexisting non-radiographic axial spondyloartrhritis and joint hypermobility syndrome, complaining of back pain with morning stiffness, enthesitis, peripheral arthralgia, high erythrocyte sedimentation rate and C-reactive protein level and positive HLA-B27. The association of these two conditions is rare, but especially interesting in view of their contrasting features, one causing axial skeleton stiffness, the other a wider range of peripheral joint movements. Coexistence of these two opposite disorders causes confusion in diagnosis and management, resulting in lower quality of life for patients, as they are in pain from the early stages. Therefore, this association is suspected in young individuals with back pain and physical exam findings of peripheral joint hypermobility and axial skeleton loss of mobility.
我们报告了两例同胞兄妹，他们同时患有非放射学轴性脊柱关节炎和关节过度活动综合征，主诉有背痛伴晨僵、附着点炎、外周关节痛、红细胞沉降率和C反应蛋白水平升高以及HLA - B27阳性。这两种病症并存的情况很少见，但鉴于它们截然不同的特征，一种导致中轴骨骼僵硬，另一种导致更广泛的外周关节活动范围增加，所以格外引人关注。这两种相反病症的并存导致诊断和治疗混乱，使患者生活质量降低，因为他们从早期就开始疼痛。因此，对于有背痛且体格检查发现外周关节过度活动和中轴骨骼活动受限的年轻人，应怀疑有这种关联。
