Qian Apan, Shi Huang, Zhu Runlang, Yan Jiatao, Li Wen, Liu Kun, Zhang Afang
Laboratory of Polymer Chemistry, Department of Polymer Materials, College of Materials Science and Engineering, Shanghai University, Materials Building Room 447, Nanchen Street 333, Shanghai 200444, China.
Org Biomol Chem. 2017 Oct 4;15(38):8028-8031. doi: 10.1039/c7ob02171b.
Monodisperse thermoresponsive cyclodextrins appended with benzenesulfonamides were demonstrated to reversibly regulate the enzymatic activity of carbonic anhydrase, which was found to be dependent on both scaffold effect and thermoresponsiveness.
带有苯磺酰胺的单分散热响应性环糊精被证明可可逆地调节碳酸酐酶的酶活性,发现这既取决于支架效应又取决于热响应性。